ID   A0A180GXL0_PUCT1        Unreviewed;       659 AA.
AC   A0A180GXL0;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-FEB-2023, entry version 16.
DE   RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN   ORFNames=PTTG_00101 {ECO:0000313|EMBL:OAV97012.1};
OS   Puccinia triticina (isolate 1-1 / race 1 (BBBD)) (Brown leaf rust fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX   NCBI_TaxID=630390 {ECO:0000313|EMBL:OAV97012.1};
RN   [1] {ECO:0000313|EMBL:OAV97012.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAV97012.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA   Yandava C., Izard J., Baranova O.V., Blanton J.M., Tanner A.C.,
RA   Dewhirst F.E., Haas B., Nusbaum C., Birren B.;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:OAV97012.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAV97012.1};
RA   Cuomo C.A., Bakkeren G., Szabo L., Khalil H., Joly D., Goldberg J.,
RA   Young S., Zeng Q., Fellers J.;
RT   "Comparative analysis highlights variable genome content of wheat rusts and
RT   divergence of the mating loci.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAV97012.1}.
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DR   EMBL; ADAS02000016; OAV97012.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A180GXL0; -.
DR   VEuPathDB; FungiDB:PTTG_00101; -.
DR   OrthoDB; 3030820at2759; -.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00159; RhoGAP; 1.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR45808; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR   PANTHER; PTHR45808:SF2; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
FT   DOMAIN          213..441
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          590..632
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   659 AA;  72340 MW;  CBF9CF41249DAAD4 CRC64;
     MKQPDTSFST ASSSESSQES SSSAATETES SSSTSSSAAL QNQLIHKIIY SAGLDHQSNP
     LLVISASSFP AKLPAHLTLD SLTQQALSLF SPIISNGPYS LVIFASPAEH APTVKQILFS
     YRQFSRPIRK NLTALWVVHP TFWAKTTVQV LLKTIVSWKM SRKIKWIKDL STLASLVPIH
     QICIPPEVYK YDLTIEPAIT VPPSFRKPPV FKVSLEELMG VEGQDGIPQV IQDCANCIRS
     SGMKFEGLFR RPPSLTTTQI IRDAYDRRQP VKMEDYADGP FLAASLIKLF LRELPQPIFP
     ADFYSLFRAC PPIYAQPIIP SHHDQSSLNT HNQAVLDYLR EHILKDLRPK PAHILLDYVL
     KLCHDLALHS EHNKMDAHNL ATCLAPTMIR SSDLISDAMM CKLPSPSSTK GSPDQADQSS
     PEPTSFICIL KFMISCYPLL FDEPQEPISP ACSSLSSSSM FKDSHSTMDL SLSSFRATSS
     ATGRTGTSSV YEGSDDPSSL FQKLFGVRRP TASYLPPLRC TISHVGLSHA FSLADRRRSR
     LLQGPAGSSS HHPDQKLLRF ATLQPPKTAT NNSLPSLSSA FIPLSRPLSP SSSSDSSTFF
     SSTSVTTTTS TTTTVNDSCP SSTHPRPLGS AANHTYQPLQ TIFDHQSRFA HSSDLNELD
//