ID A0A180H5A9_PUCT1 Unreviewed; 1105 AA.
AC A0A180H5A9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PTTG_01530 {ECO:0000313|EMBL:OAW00191.1};
OS Puccinia triticina (isolate 1-1 / race 1 (BBBD)) (Brown leaf rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=630390 {ECO:0000313|EMBL:OAW00191.1};
RN [1] {ECO:0000313|EMBL:OAW00191.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAW00191.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Izard J., Baranova O.V., Blanton J.M., Tanner A.C.,
RA Dewhirst F.E., Haas B., Nusbaum C., Birren B.;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OAW00191.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAW00191.1};
RA Cuomo C.A., Bakkeren G., Szabo L., Khalil H., Joly D., Goldberg J.,
RA Young S., Zeng Q., Fellers J.;
RT "Comparative analysis highlights variable genome content of wheat rusts and
RT divergence of the mating loci.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAW00191.1}.
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DR EMBL; ADAS02000001; OAW00191.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A180H5A9; -.
DR VEuPathDB; FungiDB:PTTG_01530; -.
DR OrthoDB; 54187at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018:SF143; PHOSPHATE METABOLISM PROTEIN 7; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 18..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 500..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 562..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 600..617
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 624..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 665..683
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 695..713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..167
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 190..394
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 405..680
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 842..908
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT REGION 739..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 951..987
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1077..1105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 739..753
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..785
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 951..976
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1082..1105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1105 AA; 122259 MW; 2C3D52A11161E24B CRC64;
MASDTSFKAA STKSTSTFIS ALIISASVAG IQVAAFLILR TSIRKIYAPR TYLPIPSKRA
QPVSVTPWGW LLPTLTSPSK SMIPTAGLDA YMYIRFLRMM IFIFAPTSCL VAVVLLPLNS
VGTSVSTTGL NSFAFGNIPA NQQIRYVGHL LCAYAITIWT VFLIQNEMSE YIQVRQRYLT
RQSHLDLPQS RTVLVTGVPK SFLSSEVLNS LTARLPGGIK RVWISRALND LPEIYKKRLE
CVSMLESAET TLVKKAIKQH RSMLASSPDG SHSILPEAIK RARSKEHSVA EEHDPVDQFV
RRKSRPSHRL GFLGLFGKKV DTIDYCKDEI VKLTNQLEEA RTKIDQHHPH NSAFIEFNEI
LAAQIFSQIV LYQKPLRMAK RYVDAAPQDI IWDNLNINPY DERVRNMISW VITLGLVILW
SFPVAFIGSL SNITSLCTTV HWLSWLCQSH NHLQDVIQGI LPPVLLALIF LILPMLLRLI
GRYSGVPRIS EIELILMTRY YIFLVIHGFV VTTLSSGLTA AIPELSKDPS KAVTILTVNL
PRASIFFMTY MITTSLTSAS GALLQIFPLI IYYLKLFVLA STPRSVFDVR YEMAQPQFGT
LFPNTTLLAT IGLAYSITAP IMSILALFAF TIYFVVYKYL FLFVYDVPAA HETGGRFFPL
AMNHVFIGLY FSQLCLTGLF FLARDVSDNA SSIPQAAMMI VLFVLTCFSH VLIRNSYAPL
TMFVPLNMLE EEVISKTKKL KQQTPSASEK QSPADRVSFP EGSAQKDWSS PASDNTNETF
VQRSCSEADM TQMSISKLDG QEFCQTVLTP IGEDAGEYLS HSQRPPLENH ANAGGHSWGE
ENFVTEQSRT AFLHPAVWEN TRPVWIPEDP IGVAKLEVLD MKARKIPASL KGAEITSSGK
VFVTRSPPEN AEVIELERNK VQGIFALPGA LGGVARAAGG TIGGRVMRSA SARTNQTHAR
NHSSSSSTQS LTNDGSAPPP AVPKLPLGID SLKTGLSALG RRKTLRPSLE ADDSRFLKHM
SDVPEETPTT AVNPGFGFEP GEDSHELHCF DHVAAAPNQS HLLLRPTEQA DHHFHSRVHS
AESSAAGCSS RPDTSPSFAY HPSDR
//
