ID   A0A180H5I6_PUCT1        Unreviewed;       739 AA.
AC   A0A180H5I6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Calcineurin-like phosphoesterase domain-containing protein {ECO:0000259|Pfam:PF00149};
GN   ORFNames=PTTG_08617 {ECO:0000313|EMBL:OAW00072.1};
OS   Puccinia triticina (isolate 1-1 / race 1 (BBBD)) (Brown leaf rust fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX   NCBI_TaxID=630390 {ECO:0000313|EMBL:OAW00072.1};
RN   [1] {ECO:0000313|EMBL:OAW00072.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAW00072.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA   Yandava C., Izard J., Baranova O.V., Blanton J.M., Tanner A.C.,
RA   Dewhirst F.E., Haas B., Nusbaum C., Birren B.;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:OAW00072.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAW00072.1};
RA   Cuomo C.A., Bakkeren G., Szabo L., Khalil H., Joly D., Goldberg J.,
RA   Young S., Zeng Q., Fellers J.;
RT   "Comparative analysis highlights variable genome content of wheat rusts and
RT   divergence of the mating loci.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAW00072.1}.
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DR   EMBL; ADAS02000001; OAW00072.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A180H5I6; -.
DR   STRING; 630390.A0A180H5I6; -.
DR   VEuPathDB; FungiDB:PTTG_08617; -.
DR   OrthoDB; 1407670at2759; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR32440:SF0; PHOSPHATASE DCR2-RELATED; 1.
DR   PANTHER; PTHR32440; PHOSPHATASE DCR2-RELATED-RELATED; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        54..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          346..458
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          94..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   739 AA;  82144 MW;  AE362FF1064E54BA CRC64;
     MAWPHNQKAS ATASGRAQKR THLEDDEDED DAQLLLPTSN GLTHKRIQRV KHSLSYILIS
     GAASFVLVIM VWLGPGLVSH DPKGIATQSN AHVGYSEDTS STGKPIIPVS ANSSSRPKLS
     VSKLPVERKP IPHHSWNPLI YDPAPITHVY VKPCMFPPWA FKSFCTPHQT AREIALYGRW
     VRVPRDLSKG VGHYYTEIYY RRAQTLDVSS LDPKPITGLQ IVDEDEESDP VIKAKLAKEG
     WEVAGESLRT GIWPTRVTDA KLYFTRSTSF MNPTDQAAVQ PINEISVLWS HKADLTKPWW
     GFERLNKPVF DGDNLIDHIQ CDISVRRQII EPPPPPALTF QKDGKFKIMQ ISDLHFSASG
     GTCQSASELE NCAKDGADGT TKKWLTKAIG EARPDLIVLG GDQLLGRDKT FDTISTLTKI
     GHFFADQKVP WTVVFGNHDV DRSLAIEEQM YLMKQMPFFL GKAGPGVPGF DDEGHPQVDQ
     LSDMGVGNYV LRVNASLADP TQLLSLYFLD SHDYPRKTFS HLWDIAMGGS SKFDWLKKSQ
     IEWYKRQSEA QPRVLQPYEA SAGYRARAAA AENAGKKSKP VGLMFFHIPL PEAYAKADLN
     PKSKAELVFG NQRESPLNAE DGDHFFEKAI RATPISDSHS NATTFEPEIK VIANGHAHAT
     DTCRQHQGVY HCFSGLASYS GTLDAKAARG WERRVRVFEV ERFGGKVATY LLKHALDSPG
     HPVVRLGSHV LFDSESTSS
//