ID   A0A183A545_9TREM        Unreviewed;       906 AA.
AC   A0A183A545;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=PBPe domain-containing protein {ECO:0000313|WBParaSite:ECPE_0000208001-mRNA-1};
GN   ORFNames=ECPE_LOCUS2080 {ECO:0000313|EMBL:VDP65350.1};
OS   Echinostoma caproni.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Plagiorchiida; Echinostomata; Echinostomatoidea; Echinostomatidae;
OC   Echinostoma.
OX   NCBI_TaxID=27848 {ECO:0000313|Proteomes:UP000050740, ECO:0000313|WBParaSite:ECPE_0000208001-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ECPE_0000208001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP65350.1, ECO:0000313|Proteomes:UP000272942}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Egypt {ECO:0000313|EMBL:VDP65350.1,
RC   ECO:0000313|Proteomes:UP000272942};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; UZAN01039404; VDP65350.1; -; Genomic_DNA.
DR   WBParaSite; ECPE_0000208001-mRNA-1; ECPE_0000208001-mRNA-1; ECPE_0000208001.
DR   Proteomes; UP000050740; Unplaced.
DR   Proteomes; UP000272942; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   InterPro; IPR001508; Iono_Glu_rcpt_met.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   PANTHER; PTHR18966:SF422; KAINATE-TYPE IONOTROPIC GLUTAMATE RECEPTOR SUBUNIT 1D; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   PRINTS; PR00177; NMDARECEPTOR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023286};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000272942};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          552..799
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00060"
SQ   SEQUENCE   906 AA;  101226 MW;  B6354522333725B4 CRC64;
     MESSGFDLVE MFDSMREDIL HDSCVSLTPK ECELIPNITF VIRSFSNSEV CSLISAGVRA
     IISMTTCSVA QEIEHVCEQY HIPHMAIPKP TCGNEINISQ AKNGIADPTG SWDKNRKPWV
     VLDVSMVVQM LRAIELTEMV SRKMIFTDGY SVIPLKVLLS ETDSILEGQP SATPSTHVFH
     LDEGLNDGER NPHTNSNSLA SYLIWLRKAL NDSDAPLSSN YYELFALNHD IERVTSVISE
     TCMLNIDQFW VIVEFSDQAP YLITKVLTES LSGRGNCNNR RANVALIRQF PLDYALSLLK
     GLYTYEEEVY VKSLSGSTKE IPERLTIAGF IVFSLSKAYV GLVKEEPSFA AEESLSCETN
     QTFTYGVRLR NLMYDRIVAS ELNSKLYLYA THTYDFKYNM EFLLTASFSG GELKLTPNGE
     TIAHESHGSG LFPNRFRGMH DTYLRIGVVI DPPFVNANGR SATGELLNVT GLIPDIMELL
     GERFKFRQLF SDISRFNQQR IDIAAALLTL TDDRSLHINY LGPFLISSTA MLGARVASDN
     SLFKMFKPFK PSVWIMIAAS VIVSGLGLFA INRLSPFSAW NLGLPGAIAD EVAVQENVWS
     TIGSFLLQGS EIFPLALSSR ALVLLFWSVV VVVHATWQAD LTAYMSRAYV QSSIRSMREL
     AYSYEYQPIA VSGSSIYGSF QSYPIRSTQE GIDAVIADPS LIFIHDKLLL RYAVSNECEK
     IQLLPITFAE AAAGFGVAKG RDFEKAFSDY LEGLQENGSI DRLINKWWFA LNICKDKEPQ
     YRQMTITDVL GAVIILSVAI GCSFLALFIE CVYVRWLRPT IMQRIRRKVS IADRSIVCIT
     EPSESNMGQS SLRRRSSMLL SILPDQIANE FRYGGRRRAI CAHNAFSVNL PSDPDITRRS
     SGSVAY
//