ID   A0A183APE5_9TREM        Unreviewed;       741 AA.
AC   A0A183APE5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Dynein_heavy domain-containing protein {ECO:0000313|WBParaSite:ECPE_0000885601-mRNA-1};
GN   ORFNames=ECPE_LOCUS8830 {ECO:0000313|EMBL:VDP84265.1};
OS   Echinostoma caproni.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Plagiorchiida; Echinostomata; Echinostomatoidea; Echinostomatidae;
OC   Echinostoma.
OX   NCBI_TaxID=27848 {ECO:0000313|Proteomes:UP000050740, ECO:0000313|WBParaSite:ECPE_0000885601-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ECPE_0000885601-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP84265.1, ECO:0000313|Proteomes:UP000272942}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Egypt {ECO:0000313|EMBL:VDP84265.1,
RC   ECO:0000313|Proteomes:UP000272942};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UZAN01046528; VDP84265.1; -; Genomic_DNA.
DR   WBParaSite; ECPE_0000885601-mRNA-1; ECPE_0000885601-mRNA-1; ECPE_0000885601.
DR   Proteomes; UP000050740; Unplaced.
DR   Proteomes; UP000272942; Unassembled WGS sequence.
DR   GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR   GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 1.20.1270.280; -; 1.
DR   Gene3D; 3.10.490.20; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR   InterPro; IPR041658; AAA_lid_11.
DR   InterPro; IPR042219; AAA_lid_11_sf.
DR   InterPro; IPR041228; Dynein_C.
DR   InterPro; IPR043160; Dynein_C_barrel.
DR   InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR22878:SF63; DYNEIN AXONEMAL HEAVY CHAIN 10; 1.
DR   PANTHER; PTHR22878; UNCHARACTERIZED; 1.
DR   Pfam; PF18198; AAA_lid_11; 1.
DR   Pfam; PF18199; Dynein_C; 1.
DR   Pfam; PF03028; Dynein_heavy; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000272942}.
FT   DOMAIN          144..256
FT                   /note="Dynein heavy chain region D6 P-loop"
FT                   /evidence="ECO:0000259|Pfam:PF03028"
FT   DOMAIN          288..434
FT                   /note="Dynein heavy chain AAA lid"
FT                   /evidence="ECO:0000259|Pfam:PF18198"
FT   DOMAIN          441..738
FT                   /note="Dynein heavy chain C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18199"
SQ   SEQUENCE   741 AA;  85379 MW;  88BE447EB367A26F CRC64;
     MTSKLEQDAG HTGTSEMDFF IKGNVSVEKT KQEKPVDWLP DSCWQDLVKL VELFPQPFET
     LARDIREHQD TWKTWYNRET PESSSLPGKY ENVVSDFQRL CLLRCFRVDR VYQAITLYVI
     KIMSETFVTP PILSFTTIYE QSTPVSPIVF ILSPGSDPTG DLVKFAERQN MDPTHIKFLS
     MGQGQEKNAQ SLLELSVARG YWLMLQNCHL LVKWLHVLEK YLESLSKPHP DFRLWLTTEP
     CGAFPIGVLQ RSLKVVTEPP NGLRQNLRST YHKIPPSAMN DCAHPAFPAL VYVLAFFHAV
     VQERRKYGKI GWNIPYDFNE SDFRVCKSIL ATYLQKAHEE GETKIPWDSL KYLIGEVMYG
     GRAIDDFDRR ILKTYMDEYF GDFIFDTFQP FHFYKNETVD YLIPEGMQRE EYMKYIESLP
     LNNSPEVFGL HANAEIGYYT SAAKEIWSKL IELQPQTSSE SSAASRDEFI SQVTKDILQT
     IPEPYDREAL RKKLGTEISP TTVVLLQELE RINLLITRMR ISLRTLTRAL NGEVGMSAEL
     DDLARSLLNG QLPQMWRRLA PATLKSLADW IIHFRDRIKQ YDNWIEKGEP NVIWLSGLHI
     PESYLMALVQ TTCRRNSWPL DRSTLFTSVT SYEDPAEVQE RAHQGCFVSG LYLEGASWDV
     AHECLVRQLP KQLIQPLPVL RITAIEAHRL KLQNTFRTPV YVTSDRRNAM GVGFVFEADL
     KTDTHASHWV LQGVCLTLNT D
//