ID A0A183C855_GLOPA Unreviewed; 1393 AA.
AC A0A183C855;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Endonuclease {ECO:0000313|WBParaSite:GPLIN_000905100};
OS Globodera pallida (Potato cyst nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Tylenchomorpha; Tylenchoidea; Heteroderidae; Heteroderinae;
OC Globodera.
OX NCBI_TaxID=36090 {ECO:0000313|Proteomes:UP000050741, ECO:0000313|WBParaSite:GPLIN_000905100};
RN [1] {ECO:0000313|Proteomes:UP000050741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA Aslett M.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000050741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA Cotton J.A., Lilley C.J., Jones L.M., Kikuchi T., Reid A.J., Thorpe P.,
RA Tsai I.J., Beasley H., Blok V., Cock P.J.A., Van den Akker S.E.,
RA Holroyd N., Hunt M., Mantelin S., Naghra H., Pain A., Palomares-Rius J.E.,
RA Zarowiecki M., Berriman M., Jones J.T., Urwin P.E.;
RT "The genome and life-stage specific transcriptomes of Globodera pallida
RT elucidate key aspects of plant parasitism by a cyst nematode.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:GPLIN_000905100}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
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DR WBParaSite; GPLIN_000905100; GPLIN_000905100; GPLIN_000905100.
DR Proteomes; UP000050741; Unassembled WGS sequence.
DR GO; GO:0042575; C:DNA polymerase complex; IEA:UniProt.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR001995; Peptidase_A2_cat.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041577; RT_RNaseH_2.
DR InterPro; IPR001878; Znf_CCHC.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SMART; SM00343; ZnF_C2HC; 2.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50175; ASP_PROT_RETROV; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 340..387
FT /note="Peptidase A2"
FT /evidence="ECO:0000259|PROSITE:PS50175"
FT DOMAIN 511..689
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 1078..1230
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 1337..1360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1393 AA; 158227 MW; BBF61CDF3DFB21E4 CRC64;
MDKNLVEILQ HLTSIVKQQN SPASGQNSVT LPDIQPFNNG EEAIDFEEWM DRFQFAIECT
APNLEEAAKV KLLMTKLSPA AFGEYKRSCL PEEITQFGFN ETKKRLQNLF SRPNSLAMDR
YDCLKACREE GEELGVFINR LKVLFRKFRY SELNEDQFKC LVLLSALKAP NEAKLRQYIL
SRLTMEETKT PKTAKLFETV TEELFTMLKT ESEVKMLEQA RPKINAVQQK QSKPTLFKKE
NWAKPNISRS AYNGKPPKSN CYRCGALHWA QNCPEFHHVC KKCNGKGHTE KMCEKIQAFR
QNKKAKSPKM NMLRLPVAHI NSLNSSKLLR AEIKTNGTPI KFILDTGADI NVIDEKSYKI
IGSPPVEKCS EEAILFDGSR CTFLGKGTTT FQFNEIQSVQ QFYVAKCGAL NLLGAATLDE
FGFLQGMKNM LSGNTTINQI SSQNIEAKIK ETITNLPQKF AQVFSEGLGL CTKMNAHLAL
KADINPVFRR ARPVPYSALS IVNGELDRLE KMKVITPVEH TEWAAPVLVV KKANGTARLC
ADFSTGLNDS LQLHQHPLPL PSDIFAKLNG GKYFSKVDLS DAYLQIELGE DSKKLCTIAT
HRGHFKYERM PFGVKSAPGI FQSIMDNMLA DLPFTLAYLD DIIIVSPSVD EHVVHIEQLF
ARLMNWGLKV RIDKCSFFQN EIKYLGVIID RHGRKPDPSK VSAIADMPIP SEVNELRSYL
GMVNYYQEFV RNFRFIRQPL DELLRKDKPW NWSNKCQDAF NKINAALQSD LALTHYDPAL
PITVAADASE HGIGGVISHQ FPNGMVKAVS HFSRSLTPAE QNYGQIEKEA LALVEAVKRF
HKMIFGRKFT LLTDHQPLKK IFGNKDGVPK HSHNRLVRWS LILTAYDFEI QYVNTEKFGQ
ADALSRLISS NRKSKAGEEI IIASCETENV LVENIHETIR QLPITFKDLV ATTKTDPALQ
QIRSFITKTW PEPKNFRETE FLPTEKFSQF HRRKEEISIV DNCLMLGERI IIPRSLQKYV
LRMLHQGHPG IKRMKSLARI HVYWPMMDSE IESFVHKCSA CALVAKNPIK TTLQSWPKTD
GPWKRIHMDY AGPFNGKMYL IIVDSYSKYP EIFEMNSTNS SATISKLKSL IARYGIPETV
VSDNGTQFRS HQFQQFTKSF GIEHLFSAPY APQSNGQAER MVDTFKRAFA KIKGEGVSGN
VLETFLLTYR TTPAEVLDGK CPAELFLGRK PRIELDLLRP RGIATRKDLR MEAQFNKKHG
ARFRSYAIDE NVFVRHLKSG AWRPGKVVER RGVIYTVEFG DQTSSRFHAN QLQLRRTDED
DGPLDILNQT FGLPLPNLEV EPPADAGPVD EAPTAEGNVR RYPARIRRPA TRLNIGDVRQ
PAYDYLAVRR SPD
//
