ID A0A183CKU2_GLOPA Unreviewed; 1927 AA.
AC A0A183CKU2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=ATP-dependent RNA helicase DDX1 {ECO:0000256|ARBA:ARBA00014916};
OS Globodera pallida (Potato cyst nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Tylenchomorpha; Tylenchoidea; Heteroderidae; Heteroderinae;
OC Globodera.
OX NCBI_TaxID=36090 {ECO:0000313|Proteomes:UP000050741, ECO:0000313|WBParaSite:GPLIN_001349800};
RN [1] {ECO:0000313|Proteomes:UP000050741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA Aslett M.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000050741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA Cotton J.A., Lilley C.J., Jones L.M., Kikuchi T., Reid A.J., Thorpe P.,
RA Tsai I.J., Beasley H., Blok V., Cock P.J.A., Van den Akker S.E.,
RA Holroyd N., Hunt M., Mantelin S., Naghra H., Pain A., Palomares-Rius J.E.,
RA Zarowiecki M., Berriman M., Jones J.T., Urwin P.E.;
RT "The genome and life-stage specific transcriptomes of Globodera pallida
RT elucidate key aspects of plant parasitism by a cyst nematode.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:GPLIN_001349800}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX1 subfamily.
CC {ECO:0000256|ARBA:ARBA00008765}.
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DR WBParaSite; GPLIN_001349800; GPLIN_001349800; GPLIN_001349800.
DR Proteomes; UP000050741; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR CDD; cd12885; SPRY_RanBP_like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.90.1440.10; SecA, preprotein cross-linking domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000185; SecA.
DR InterPro; IPR011115; SecA_DEAD.
DR InterPro; IPR014018; SecA_motor_DEAD.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR044736; Vid30/RanBPM/SPLA_SPRY.
DR PANTHER; PTHR30612:SF0; CHLOROPLAST PROTEIN-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR30612; SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; 1.
DR Pfam; PF07517; SecA_DEAD; 1.
DR Pfam; PF00622; SPRY; 1.
DR PRINTS; PR00906; SECA.
DR SMART; SM00957; SecA_DEAD; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51196; SECA_MOTOR_DEAD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 3..634
FT /note="SecA family profile"
FT /evidence="ECO:0000259|PROSITE:PS51196"
FT DOMAIN 116..256
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 488..639
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1213..1408
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 1591..1679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1123..1234
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1927 AA; 213581 MW; 416EAF8A492D0A26 CRC64;
MSNSIGAVIG GQNEYGNSKS GEELLVELWD LNHNVEAISI DWLAQMVKDV YKWIRQAGGI
SKWAAEDIKS WAEDLKKQRQ AHELPELLAV ACRACKLANG YYPRTAQLIS ILLMLSSSKA
GRRGHLQQIA TGEGKTAIVA LFVVVKALRD RVKIDVLTSS KALARRDAKD LKTFFGMFAL
TVDDCTGGLS PRYKGCYAAD ILYGDIGSFQ GDILCHEFQS KNVRGTPPRP FECIVIDEVD
CMLVDDMMQG KVLMLSFHVP GMEYLEGILM MCWEHFVQFW SDLKRDPEDE NILIQQIDGE
DYRAEAWQHY ENFVRHLETQ LTNLINENGG TLVIPPHLRA FALKQIPKWM SALKKAIKMN
ENCEYVIRED AGGKKVVVPI DYQNTGTQQR STSLSDGLHQ FLQLKHGLRM DPETLVTSFI
TNPGFINRYK QIYGLSGTLG SNFEHSFLKE HYNVDITLMP TYKQPQLETM TPIIENDQQS
WIDKICESIS VQVTLCKRAA LIICLTNDKL KQLSTVFKSR HPGSYKYTDD DEHFPTEFVG
PMDVIFSTNY AGRGTDIKTN AELEANGGLH VIVTFMPRNS RVERQAFGRT ARQGKKGTAQ
LILNKCDMDR DLFDQNMDIL AKRDQLVEQS FEESKNEVLP KLLVKERLFE KFSTFIEEIR
KSTTNAVGGN EQILAQIEEH WGFWLREKVE MRDADAPMPL EAVLLSELDA FIVEERRKGS
PPPRRPPPAE FRPFGGASLF SSFFAPMMMA RALSSSSFRC EAPFLGLNIF TNPSYLVLKG
YSLDYKNAIA HLEKAIKLDV HNSGFSALAH YYMALALVKK GDDISVNERE VRAEHQNKAA
EHLKKANELI NEKLIPWLSR GAIMRPNSAF SQQNVNKVQL LKRLSEQCEK WYNFISECPA
GHFCKFNGWI KPDPDKKLPE AEVDEFGKFG VWEFYQLEYA KPPKAWASIG LMAFFGAVQF
GIGVWCVCTG NFRLALPFLQ SGIRDLVEAA RAAIGNTVIS WSTFAIDKIR TYGAALAGWT
NSLLSTCKDG IGKWLFKCAN WLGLAKPLET PTTGKGDFLT KVIVNSELKQ YLWPTFANLD
PSEEVRRLRA RIAELNRQEM LFSPISSASF DLMAQNGNEV GDADTLDDQN EIEEKMKMEL
EEELKKEKQL QEELKNAEKS IGRKLEQMEE WNSNKNSAKK TLLERLKELE QKQTANSEQQ
KADQKALNAM KKYQKQQQQT IDTLTQKLKG LTQNRWNSAA CHNGLALSGP DRLIVQHFGE
KEAWISVFAE EPIPKKDSGI FYYEVKMLGM GAVVIGLAPK QMPLNKTVGD FKGSYAYQSH
GNFFGHAVDG CFRSDFGRPV IGGKPPFGVR DVIGCGVNLA TRQIIYTKNG NRLDAVGLTQ
LARRSWPDAV GSDAVGPKTQ LARRSWRDAV GQTQLARRSW PDAVGQTQLA QTQLAPRRSW
PDAVGETQLA QTQLAQTQLA RQLVGTRKTI GNTYNRKGRL LDQKFVSEQT RMSMPQLNLV
AGLIHQGVAA PLGKDSIQIL FEIGDNYFRD TVKEEMSRKI AAVAREVFGD GGDFLKNWAE
ATFVQLFTDK CAEELDKFAD KIFADVYSTN NGGEAGTSNR PSNNGSGAGA SNRPSNNGSG
AGASNRPSNN GSGAGASNRP SNNGSGAGAS NGPSNNGSGA GTSNQLMNVG GGAGTSNRPS
NNADICRRAA QLLLTGLHDS GWAYLTTTIG GAGASNQLMN IGGGAGPSNQ LMNIGGGAGP
SNQLINIGGG AGPSNQLINI GGGAGPPNRP TDNDEPNFTD LVLLAIDCEC VGVGPGGKKD
MLARDSTNSE ISNGRGNEQI LAQIEEHWGF WLREKVEMRD ADAPMPSEAV LISELDAFIM
DERRKANNLS IFTNPSYLVL KGYGLDYENA IEHLEKAIEL DEHKSGFAAP AHYYMALALV
EKGDHFR
//
