ID A0A183E2J7_9BILA Unreviewed; 176 AA.
AC A0A183E2J7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=E1_dh domain-containing protein {ECO:0000313|WBParaSite:GPUH_0001520801-mRNA-1};
GN ORFNames=GPUH_LOCUS15186 {ECO:0000313|EMBL:VDN25526.1};
OS Gongylonema pulchrum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Spiruroidea; Gongylonematidae; Gongylonema.
OX NCBI_TaxID=637853 {ECO:0000313|Proteomes:UP000050760, ECO:0000313|WBParaSite:GPUH_0001520801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:GPUH_0001520801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN25526.1, ECO:0000313|Proteomes:UP000271098}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; UYRT01082131; VDN25526.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183E2J7; -.
DR WBParaSite; GPUH_0001520801-mRNA-1; GPUH_0001520801-mRNA-1; GPUH_0001520801.
DR Proteomes; UP000050760; Unplaced.
DR Proteomes; UP000271098; Unassembled WGS sequence.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000271098};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 102..169
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 176 AA; 19618 MW; FA4E0F037B6CD639 CRC64;
MMNVISNIFK AAKVPVQQQP FIAFSFRLLS NEASFQTKPY KLHRLESGPS ANVSVTRDDA
VDYYRKMAKI RRMETAAGNL YKERLVRGFC HLYAGQGHGR RTGNVHGKGG SMHMYNKNFF
GGNGIVGAQQ AIGAGLAFAQ KYNKKKNVSF TLFGDGAANQ GQLYEGCYFW CVSKMH
//
