ID   A0A183EBW5_9BILA        Unreviewed;       302 AA.
AC   A0A183EBW5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-FEB-2023, entry version 21.
DE   SubName: Full=PAP2_C domain-containing protein {ECO:0000313|WBParaSite:GPUH_0001848101-mRNA-1};
GN   ORFNames=GPUH_LOCUS18455 {ECO:0000313|EMBL:VDN31781.1};
OS   Gongylonema pulchrum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Spiruroidea; Gongylonematidae; Gongylonema.
OX   NCBI_TaxID=637853 {ECO:0000313|Proteomes:UP000050760, ECO:0000313|WBParaSite:GPUH_0001848101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:GPUH_0001848101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDN31781.1, ECO:0000313|Proteomes:UP000271098}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the sphingomyelin synthase family.
CC       {ECO:0000256|ARBA:ARBA00005441}.
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DR   EMBL; UYRT01086794; VDN31781.1; -; Genomic_DNA.
DR   WBParaSite; GPUH_0001848101-mRNA-1; GPUH_0001848101-mRNA-1; GPUH_0001848101.
DR   Proteomes; UP000050760; Unplaced.
DR   Proteomes; UP000271098; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR045221; Sphingomyelin_synth-like.
DR   InterPro; IPR025749; Sphingomyelin_synth-like_dom.
DR   PANTHER; PTHR21290:SF25; SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1; 1.
DR   PANTHER; PTHR21290; SPHINGOMYELIN SYNTHETASE; 1.
DR   Pfam; PF14360; PAP2_C; 1.
PE   3: Inferred from homology;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271098};
KW   Sphingolipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        54..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          116..165
FT                   /note="Sphingomyelin synthase-like"
FT                   /evidence="ECO:0000259|Pfam:PF14360"
SQ   SEQUENCE   302 AA;  35324 MW;  E221469FE5E3747F CRC64;
     MKTYPPLPDI VLDNMPLVPW AFDVCEMIAV CLAALWFTIL FFHKHRVVVM RRMFSLVGTV
     FLLRCVTMLI TSLSVPGVHL ECRSKSYGTF SARLQQAYHI WSRFGMSIQG VRSCDTPDSW
     HGLHTVTWVL NLFGIFFILA GHEHYSIDVF IAFYISSRMF LYYHAYAYHQ FSLTSTENRM
     RAWFPLGWFF EAGGQGRVEN AFDVPLYVPV ITFPEFRKYL HSEGKKAKNV PEKKPIPKLV
     LDLNNGSLAD KHXXXXVRKV YFFRFDLLVL MSSRRINLGL FHLSFFDFSF QYVQLLFNKL
     YK
//