ID A0A183GYI2_9BILA Unreviewed; 439 AA.
AC A0A183GYI2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Mitochondrial import receptor subunit TOM70 {ECO:0000313|WBParaSite:OFLC_0000029101-mRNA-1};
GN ORFNames=OFLC_LOCUS292 {ECO:0000313|EMBL:VDO25278.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0000029101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:OFLC_0000029101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO25278.1, ECO:0000313|Proteomes:UP000267606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004572}.
CC -!- SIMILARITY: Belongs to the Tom70 family.
CC {ECO:0000256|ARBA:ARBA00038030}.
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DR EMBL; UZAJ01000085; VDO25278.1; -; Genomic_DNA.
DR STRING; 387005.A0A183GYI2; -.
DR WBParaSite; OFLC_0000029101-mRNA-1; OFLC_0000029101-mRNA-1; OFLC_0000029101.
DR Proteomes; UP000050787; Unplaced.
DR Proteomes; UP000267606; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR46208; MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70; 1.
DR PANTHER; PTHR46208:SF1; MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 66..99
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 355..388
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 439 AA; 49732 MW; B2888AFBF2D94A5E CRC64;
MTEKEWSSIR WSKWIVVGGA CIASSAAIWW YMRKQSRNAV SGSKSGVRPT ASVAPCPMLF
PGMQSSQEIK DKGNEYFKQC SYRKAAEAFT EAINLCPPEY KNHLAVCYQN RAAAYDRMGD
PEQSIIDCTK ALELDPLYFK AVVRRAKAYL SLSKPEQALD DLTYAFVMNP DASESLKMDV
DSAVALAAAN LVEHVKNTRE SIPVRDELVL LWRSSYVNDP ILHDLKEESL SVSPYHQALE
AIRQRHYEEV IPLVENDLVV QQSDPNQLNI TNILRDYILQ ARFALMKENV LSLKERLAAF
DSMWNTLNED SRREMINKRF RSMYHILLAA WKILEHCGDI ESEFHHAVEI DQTNVDIYLG
AALLLSENGQ LQEAIDYLDQ LNKIDPAHHL VKHMKANCTM ALKASVGDVG GAMACMTKVD
QLLQMNRNAD PILYLITGR
//
