ID   A0A183K793_9TREM        Unreviewed;       788 AA.
AC   A0A183K793;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=ATP-grasp domain-containing protein {ECO:0000313|WBParaSite:SCUD_0001087001-mRNA-1};
GN   ORFNames=SCUD_LOCUS10870 {ECO:0000313|EMBL:VDP41930.1};
OS   Schistosoma curassoni.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6186 {ECO:0000313|Proteomes:UP000050789, ECO:0000313|WBParaSite:SCUD_0001087001-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SCUD_0001087001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP41930.1, ECO:0000313|Proteomes:UP000279833}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dakar {ECO:0000313|EMBL:VDP41930.1}, and Dakar, Senegal
RC   {ECO:0000313|Proteomes:UP000279833};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the synapsin family.
CC       {ECO:0000256|ARBA:ARBA00008243}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UZAK01034048; VDP41930.1; -; Genomic_DNA.
DR   STRING; 6186.A0A183K793; -.
DR   WBParaSite; SCUD_0001087001-mRNA-1; SCUD_0001087001-mRNA-1; SCUD_0001087001.
DR   Proteomes; UP000050789; Unplaced.
DR   Proteomes; UP000279833; Unassembled WGS sequence.
DR   GO; GO:0008021; C:synaptic vesicle; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:InterPro.
DR   Gene3D; 3.40.50.20; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR016185; PreATP-grasp_dom_sf.
DR   InterPro; IPR001359; Synapsin.
DR   InterPro; IPR020898; Synapsin_ATP-bd_dom.
DR   InterPro; IPR020897; Synapsin_pre-ATP-grasp_dom.
DR   PANTHER; PTHR10841; SYNAPSIN; 1.
DR   PANTHER; PTHR10841:SF17; SYNAPSIN; 1.
DR   Pfam; PF02078; Synapsin; 1.
DR   Pfam; PF02750; Synapsin_C; 1.
DR   PRINTS; PR01368; SYNAPSIN.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF52440; PreATP-grasp domain; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000279833};
KW   Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT   DOMAIN          167..266
FT                   /note="Synapsin pre-ATP-grasp"
FT                   /evidence="ECO:0000259|Pfam:PF02078"
FT   DOMAIN          269..477
FT                   /note="Synapsin ATP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02750"
FT   REGION          34..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          87..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          507..773
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        87..105
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        527..580
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        595..767
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   788 AA;  85846 MW;  AC02EDEF6F176644 CRC64;
     MITYLKRRFS SGDLQGELAD KRMQEGLPSF LRFGSTTQSG QSYQQYQQQS SNIQTTGQGY
     SNQPQDFSST GPANYDMRYG STAPTMAEQF SSSQTATTTA NHTPGSVGRG RGAYPSAPTS
     PTRGMGLGAS LMGPMGSLTG QISNTLMRSF NTAASTAQNI SGKMSSKDHQ KILLVIDDTQ
     TDWCKYFRGK KLMGDWEIKV EQAQFSEISM TAYSEQGCVV SIYSDQIRSK PLKSFKPDFV
     LIRQHPSDLK ENWQPILTGL MYGGTPCMNT LHAIYNMKNR PWLVSLLEFL FAHLLMIRNR
     LGKENFPLIS QTYHTSHKEM VVAPAFPVIV KVGVGHRGEG KVKADTPFIY QDLVGLMISG
     QTYATTEPFI DANCDLHVQK IGTNYKAFMR KAISGNWKSN TGSALLEKVP MNDKFKIWID
     EVSRLFGGLD ICSIDALQSR SGEYFIYEAN GSDMTLYGDS QETDRTEIAE LVMQRMQSIT
     YSSSIPKVPS LQTIGRTSET ERPVGIGIGS ATPAAQPSIG PSAVHPTYNP PFQQLPSQPY
     SQVHQSQPVN VQQSLQPQVT QKYPPSTGIT SNTNSLIGEP IGSVSPALSK HSDPGFVTSF
     GSPTSSLSSR ADTPHQTSFS TPATTAASRG HSTASENSDI GYRSNIGGLS SMQNTTHTNY
     SSHTWDQSSS SGLFSPSKIP PMDSTTKPNL MNQQPSAGFD ASDHTTGTKM MSSPQQSFGS
     SFSSNVPYST EKLGNDVSRK PTGQTTSGLD RPNVPPRQTS LRTGPSTEDT DDTMKNLRKT
     FAGIFGDL
//