ID   A0A183L8Y8_9TREM        Unreviewed;       505 AA.
AC   A0A183L8Y8;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
OS   Schistosoma margrebowiei.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0000026201-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMRZ_0000026201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR   AlphaFoldDB; A0A183L8Y8; -.
DR   STRING; 48269.A0A183L8Y8; -.
DR   WBParaSite; SMRZ_0000026201-mRNA-1; SMRZ_0000026201-mRNA-1; SMRZ_0000026201.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   CDD; cd00054; EGF_CA; 2.
DR   Gene3D; 2.10.25.140; -; 1.
DR   Gene3D; 2.10.25.10; Laminin; 2.
DR   InterPro; IPR001774; DSL.
DR   InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR   PANTHER; PTHR24033; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24033:SF151; PROTEIN EYES SHUT; 1.
DR   Pfam; PF01414; DSL; 1.
DR   SMART; SM00051; DSL; 1.
DR   SMART; SM00181; EGF; 3.
DR   SMART; SM00179; EGF_CA; 2.
DR   SUPFAM; SSF57196; EGF/Laminin; 3.
DR   PROSITE; PS00010; ASX_HYDROXYL; 2.
DR   PROSITE; PS00022; EGF_1; 3.
DR   PROSITE; PS01186; EGF_2; 1.
DR   PROSITE; PS50026; EGF_3; 2.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW   ProRule:PRU00076};
KW   EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW   ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        309..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          115..152
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   DOMAIN          221..257
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   DISULFID        142..151
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT   DISULFID        247..256
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ   SEQUENCE   505 AA;  58029 MW;  E74A63669C660867 CRC64;
     LYVKIEVWDA DYSFSDLDDH LTTFEDNAFT FTVYPFETGD SSLLSPYRYH KISLNITQDY
     INMYVAVWAV CNRGSYGSDC SVNCVPQKRV RHYGCDISTG AKVCIPGWFG DECNKVDHCG
     ILTPCGPMGT CTNTHVGYTC SCKHNFTGPH CSEPPNQCSP LQDFCQNGFC LLKYLDEENR
     SLSNPIPYCV CIPGFTGKWC ELDIDECSLK PNNNGSNKSI NINHHITSSC SINSMCENLY
     GNFRCFCQNQ WTGLRCNTPP TLWPDHYKPV VNSNGLPDFI NFKRINLSTV SLENNNDDLI
     VIEKANNNWI YVLISVFIVL CLISCGILYY VCWRQKRLCG FYRMGWNREP IISKVLFTTK
     PTSSNLSREP TILCNQTPPT PQRSITKLTF IPRYNIPIQS EKYQSTIYDE IPDCFLQEKT
     QLTTNIPISK SQLSIYEPYS QLEYDTLDMT IETKYTNHHE IINNSDYIDN QIHKMTYQNS
     KNLKQEQELV LTNCMYLEPK TTSFY
//