ID A0A183LC44_9TREM Unreviewed; 605 AA.
AC A0A183LC44;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=PH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SMRZ_LOCUS1369 {ECO:0000313|EMBL:VDO51061.1};
OS Schistosoma margrebowiei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0000136801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMRZ_0000136801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO51061.1, ECO:0000313|Proteomes:UP000277204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zambia {ECO:0000313|EMBL:VDO51061.1,
RC ECO:0000313|Proteomes:UP000277204};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UZAI01000299; VDO51061.1; -; Genomic_DNA.
DR STRING; 48269.A0A183LC44; -.
DR WBParaSite; SMRZ_0000136801-mRNA-1; SMRZ_0000136801-mRNA-1; SMRZ_0000136801.
DR Proteomes; UP000277204; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045258; ACAP1/2/3-like.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23180:SF160; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1; 1.
DR PANTHER; PTHR23180; CENTAURIN/ARF; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}; Reference proteome {ECO:0000313|Proteomes:UP000277204};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 308..472
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 550..605
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 505..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 67947 MW; A263717F03BBACF4 CRC64;
MNVEMSAGLE FAQCFDDTSA VLDDFVSKFA SPLNRFGAFA DSPELHQTLA HAELAICRIR
AYYNLIQEIC QQSVITGEAF SSSLFKLAKC IGLGLDQKQS WSFNSNLSRE WNNCGTQKIL
NHATHLTSLF AEQTRRLATK ISDIEHILSK NNDSLNKLHD LRTNFQRAYD HLDNVINRAA
SVNSTRSPMD LQLFDNQVKE AQEIYQRTAI GYLSHLRQVI GPNYIISYMR LIILALSVQQ
SYSEQLGLLF NSSSKTNSLT SSILVQQCKQ LITSFEQKTN TEVPSKIKPS ETAAVEIKAI
KNLNNPPNPR LEGYLFKRSG KKGWRTWSRR WFRVHENQLV YCKRFHGLTS TDLQSATDTV
SMELNRRVCT SVSNTNGIVN KQPESGFLTQ LLCQANPQWT VMVTDLRFCT ARITQPNKRL
TAAEKPINLL NNSTDRRFVF EVISSGHRTY YLQAINVNEL DIWVNTLRSG FHDLCQTSEP
HYLKNGTAKE NFVSNSLDLL TSRSPTQNSL DFSNSPTTSS VSGFPDGRTN DHLAQVSHSS
ISGHDVLNNK SGILLWREPD LSGNRYCADC SVGDARWASI NLGVTLCTLC AAVHRSLGVH
ISKVS
//
