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Database: UniProt
Entry: A0A183MSI1_9TREM
LinkDB: A0A183MSI1_9TREM
Original site: A0A183MSI1_9TREM 
ID   A0A183MSI1_9TREM        Unreviewed;      1599 AA.
AC   A0A183MSI1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-NOV-2017, entry version 7.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|WBParaSite:SMRZ_0001900701-mRNA-1};
OS   Schistosoma margrebowiei.
OC   Eukaryota; Metazoa; Platyhelminthes; Trematoda; Digenea; Strigeidida;
OC   Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=48269 {ECO:0000313|Proteomes:UP000050790, ECO:0000313|WBParaSite:SMRZ_0001900701-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000050790, ECO:0000313|WBParaSite:SMRZ_0001900701-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SMRZ_0001900701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
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DR   WBParaSite; SMRZ_0001900701-mRNA-1; SMRZ_0001900701-mRNA-1; SMRZ_0001900701.
DR   Proteomes; UP000050790; Genome assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   Gene3D; 1.25.10.30; -; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR035910; IP3R_RIH_dom_sf.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 3.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   Pfam; PF02026; RyR; 2.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 1.
DR   SMART; SM00449; SPRY; 2.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 2.
DR   PROSITE; PS50919; MIR; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000050790};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050790};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN       92    147       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      164    222       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      434    647       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      863   1062       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   1599 AA;  176519 MW;  DFB962AF98D5BB02 CRC64;
     MVLGGDVVRL FHGDESLTAA CATESEEFSS SVAMTMNGSA PGSPPNKIQR SSIVNSDLLS
     GSRHAVMYEI GAVSTSARSL WRIEHKKTKW SAGFFSWGSE IRLRHVTTGR YLGVLPSEAN
     GSGHCDVVTL SAHEATNAAS IFLIRPSKDD KKRSEEHETE GMGEPDLRLG ETLAYLQHAA
     SGRWLSYEAY ETRKRGVGRV EEKKAVLLIE GHMDDLFSLV RAQDEEIRSA SAIRRCTSVF
     NNFIHALNYI SSPQNITLPS QQSQCNLSSG HLLGEVTQCL EDLIEFFAQP HPHEEHEIQQ
     SKLTALRNRQ NLFQNEGMIG HVLSTIERFT GTFQTRREFS QAVGEDKADQ FDELGNYLYL
     LLAALIRGNR ENCAQFATPT RLDWLFNRLE LQQGFAEGVL DALHCVLTDS DEALYLITER
     HIRTLIGLLD KQGRDPRVLQ ALCSLCLGRQ GGAVRLNQEL IYETLLPQKD LLLQTKLVDQ
     CGSVRPNIFV GYKDGGAMYP KWYFEVIIDS LETVTHQPAK IRVGWANTEG YNAHPCGGPG
     WGAAGLGDDL FSYAFDGSCL WAGGKPKRAT IGTDEATNEE ATSNVPLKRG DIIGCLLDLT
     GPVIQFNVNG RLVRGYFQDF NISGLFYPCM SMNAKASARF LLGSNQGRLH HGPPPGYSPI
     YYARQPGQKL RLEPVFTFGQ LDKYVFTGPL NSPTPQQYVF VPRTVRTSHI QLPNYVEMVR
     DRLAENLHEM WSMRKIDQGW KYGERRDDEN NLHPCLTTFD KLPPSDKQYN VTLAYETLRT
     IISLGYNITY EPLPEGTRMR TMKLSNSFTQ VNGYKPQPLD LTQIRLSVRI EALVDQLAEN
     THNMWARDRI ALGWTYGFVE DHSQKRSPHL VPYSEVDPII QQSNKDTAIE TVKTLIAYGY
     SLEPISSDSS DPGRGNSNMD YSGPTRTYRG QTTRAVTRGK WYYEAEILTS GFIRIGWAKK
     SAPPDLIIGS NSSSYAFAAH QARKWNRNGS VYGTICRPGD VVGCMMDLVD KTICYVPAFS
     LGSGQQVKIN YGNDVQSLKF FTYCGLQEGY KPLGVNMCRP LPMWYSREDP SLFVDVDRQH
     PSLKVNVSSG TTPTFKVTVK QADHMSSEEI QFLRLSLGTQ CKDHFTSKTL NERHAHLDAL
     RRQLEPEPIY TQGVGVGDSS NLIMMGQDMS ASTLEVRDRR GKKIRLGNMF KKARSRDPSP
     EVTSTLGGGG GGSLLSGGGS SLTGGKRGGA HATTGSLGPS GGGGQGSAGS GSLLSATAGG
     FSTGITGPQV TTTQMSQLYQ NPPGAISGQR QVQQAGMQAP GALGDIKDTR ATGLDDMDLF
     LPTSSGHTSP LANLVDEFSF TVLVLPGQDP GLVHIGWVTS YFKLAKTSKP DHISGFLHNV
     SSQLQFDTTH GQLHGHSNQN PMLGDTSGSG MQPYAADLFT VRQAAVCLLE SDLTLKSAVA
     ERASFMVNLG QLLNQMATAE DLGKRMSQGL SLTCWVDIAS GTLGFDLNGR DSGIRFQVEP
     STRLFAAVFY RPTVKEAIHF EFGRRNRYTL PITASMLRPP RYTSTVLPHR LRVQALEISE
     LRGWGTSIEY PVSEIAVRLP ESDRCFIALE LEEMPELLK
//
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