ID A0A183NX45_9TREM Unreviewed; 807 AA.
AC A0A183NX45;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=XPGI domain-containing protein {ECO:0000313|WBParaSite:SMTD_0000668001-mRNA-1};
OS Schistosoma mattheei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=31246 {ECO:0000313|WBParaSite:SMTD_0000668001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMTD_0000668001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A183NX45; -.
DR STRING; 31246.A0A183NX45; -.
DR WBParaSite; SMTD_0000668001-mRNA-1; SMTD_0000668001-mRNA-1; SMTD_0000668001.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR PANTHER; PTHR16171:SF7; DNA EXCISION REPAIR PROTEIN ERCC-5; 1.
DR PANTHER; PTHR16171; DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED; 1.
DR Pfam; PF00867; XPG_I; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00279; HhH2; 1.
DR SMART; SM00484; XPGI; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022759};
KW Nuclease {ECO:0000256|ARBA:ARBA00022759};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 483..560
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 347..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 760..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..365
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..411
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..794
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 807 AA; 91863 MW; 0720D8FFDEF5CE4E CRC64;
LTLKRFFKDA FYSSDKKFSG VDLDSDAFRA LPLPAQLRVV QLLREILDSS SCRNNLVQFD
DEAQFSPEQF SDVQMKRLLL RRRLAERQQE LSDNLTKQEA VQQILQLNNS MMKNILTNQS
LFSTLPFSNT TQPTTASETT ETIATAMRIQ SQDVGHAILI KKSPVNQLDE RTKLPSSTTL
NLEKLITYNT ENLNVSDECK KVEISKEDQN KEIHNDGYMS ENLCSTQETN ISTNENIVYN
SECTPIKLVN IEEYSDEHQV SILSHVTDNK SQLNDNCENY NQPLTKNSLN ANMSNDFLPE
SSSTIPKFDK SSEFIELPIP EHSCDLMGVK NDEIIAEINV LSSDIHESES LQVPHQDKYD
EIKSSSDDND DDDDFIEVET HEQVEISNTS TDSNSSQEYS VDENNVQNED KLNSVFTEEE
LTSKKVSYET NQQEAVLSSE LVVDDYTIDD DSDDVLREKA DRLIRQAQST TTRCISEAQD
LLHLFGFPFV VSPEEAEAQC VALQRHGLVD LVASDDSDVW PFGVKLVCRH LFGTGGGDNL
KRTTNPSIYK LDEVKRKLGL TIENILRLTL LCGSDYTHGI DQVGPVTAIE ILSEFDDGDD
YSLNCEINNW LHGVVNEPSE KLLHDILQPL EQFTFFLLHT CEYLIGMEYK TEAILASVLK
HRQKMELGDP REMLSSKSLI TNFFQIENQK VCQKSEIASH PVDSSELDEV TVPSKRVRHA
ASRLRNQRTT DRFFDAPSTS QHTALVRDEN NVLSELPKLR QPRRRQSVKK PPNQTKTLPE
KKRKEKAQIK PQRRVLERVC LSEEDED
//
