ID   A0A183QR49_9TREM        Unreviewed;       574 AA.
AC   A0A183QR49;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=CULLIN_2 domain-containing protein {ECO:0000313|WBParaSite:SROB_0000614301-mRNA-1};
OS   Schistosoma rodhaini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6188 {ECO:0000313|WBParaSite:SROB_0000614301-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SROB_0000614301-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   STRING; 6188.A0A183QR49; -.
DR   WBParaSite; SROB_0000614301-mRNA-1; SROB_0000614301-mRNA-1; SROB_0000614301.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 3.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          216..446
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   574 AA;  66684 MW;  3DED041B2C081764 CRC64;
     MCQILDEIHK ERCGEAIDRQ LLRTVIRMLV DLKLYDSIFL AEFLCKSQQL YAYEADTLSR
     QLSVPEYLXX XXQKNHRGRR LVVYLDSNST RSLLISTLVS ELLTRPLDYL LDNGLVNPLK
     TKQTSQLSLL FSLVSRVPNG IEKLRTHFRN YIIQMGREMV ENPTHDPEKD RNMIQNLLDS
     RDFLSEITVS CFSNDPSFMR VLQEAYEEFI NQRPNKPAEF LAKYLDSHLR SGNKAQTXXX
     XELDKLMAMI LFRFIDGKDI FEAFYTKELA KRLLLNKSAS VDAEKAMLSK LKQECGPNYT
     RKMETMFQDI ELSKQLSKNF RLSLPDTYAI ELSVNVICPA SWPPYPQTTA NYPPEMVTLR
     EEFTRFYLSH HQGRKLIYEP SLGTCVVKAK FPMTPNLRKE LQVSELQALV LLQFNQSDNA
     PITYTTIAEN TGIEEKELKR TLLSLAAGKG QRVLKKTPGN LEIENDHQFI FNTEFHHRLT
     RIKFNQVQLK ETEQEQVATE ERVFADRVAH VDCCIVRIMK TRKTIDHNSL LSEVYKQLQF
     PLKASDVKKR IENLIERDYM KRDSSNAATY HYVS
//