ID   A0A183RE02_9TREM        Unreviewed;       316 AA.
AC   A0A183RE02;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Non-specific protein-tyrosine kinase {ECO:0000313|WBParaSite:SROB_0001422901-mRNA-1};
OS   Schistosoma rodhaini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6188 {ECO:0000313|WBParaSite:SROB_0001422901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SROB_0001422901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A183RE02; -.
DR   STRING; 6188.A0A183RE02; -.
DR   WBParaSite; SROB_0001422901-mRNA-1; SROB_0001422901-mRNA-1; SROB_0001422901.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   CDD; cd11850; SH3_Abl; 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR19969:SF23; SH2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR19969; SH2-SH3 ADAPTOR PROTEIN-RELATED; 1.
DR   Pfam; PF00017; SH2; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00252; SH2; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50001; SH2; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          53..119
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          167..257
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   BINDING         312
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   316 AA;  35887 MW;  5220E82EF85AAF8E CRC64;
     MGAQHTKERP RRTYHPKVDH ELQINTSTSW IQNHNPPTNF KGSVAHTSQI NQPSDQLLIA
     LFDFTPPNTL ENQSQVRVEK GDRLQLFGYS ADGDWSDVEC IRTNERGWIP TNYTGRIPFP
     PNDHSTTLNT GSASGSSLTF QHTSSHDVSC NGSQGSLARV GLESEKWYHG AIQRSYAEYL
     LNSGITGSFL IRESESHPGQ LTISLRYEGQ IWHYRIHRDD SNMYYVIESN KFTSVSDLVH
     HHEKHSDGLA CTLLYPAPKR DRTSSELRMD PSFDIREIDR TEIVMKHKLG SGQYGVVYEA
     VWKPYNVLVA VKTLKV
//