ID   A0A183RGU4_9TREM        Unreviewed;       924 AA.
AC   A0A183RGU4;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS   Schistosoma rodhaini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6188 {ECO:0000313|WBParaSite:SROB_0001523101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SROB_0001523101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR   AlphaFoldDB; A0A183RGU4; -.
DR   STRING; 6188.A0A183RGU4; -.
DR   WBParaSite; SROB_0001523101-mRNA-1; SROB_0001523101-mRNA-1; SROB_0001523101.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF119; ATP-DEPENDENT RNA HELICASE A; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        266..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        482..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          17..183
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          261..431
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          904..924
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   924 AA;  104417 MW;  D6B32C309B5C556F CRC64;
     MDERAQLPVN PYRVSILETV RRNKVTIIRG ETGCGKTTQI PQFILDSYLE SGIGAECSIL
     VTQPRRISAI SLAERIAYER GETVGTSVGY CVRFETVYPR PYGSILFCTV GTMARKMEGG
     LRGVSHVIVD EIHERDVNTD FMLILLREMV RANRNLRLVL MSATIDITMF SEYFGDCTVL
     DIEGRTHPVE YYFLEDCIKM VNFVPPPVDE KKRKRRQELE SVTDNAEENC NLKCDPVYGE
     AVVRSMGEIT EKEVPFELVG ALLDKIIGMN IPGAVLIFLP GWNIISLLRK YLQSHSRYGS
     PNYVILPLHS QIPREDQRLV FRSTPSGVRK IVLATNIAES SITINDVVFV IDFCLSRTKL
     FTARNNLTSY STSWSSKTNL EQRRGRAGRV RPGFAFHLCS RARFDRLEQH ATPEILRTPL
     HELALLIKLL RLGSALQPPP LDAVIEAEHT LKEMKALDKN DELTPLGFIL ARLPIEPRLG
     KMLIFACVFN LGGAAAVLTS TASLGCDPFL LPPDHRRLTN QQRSFAAGYS SDHLAGLNVF
     QEWTTERTRR GDESADLFCD QHGFNSSALR VIDDAANQLR AILINLGFPE ESLSDAPVNF
     NLKHNIDCDI LSTLLVSGLY PNICFHSDKR KLLTTEGTLA LIHKSSVNCM KDIKFNYPFF
     VFDEKIRTQA VSCKGLTMVH PIQLMLFGCR SAIWRSDDSS DIGIVVIDDW IPFRMNFMTA
     ARIFAFRPAL EALLVRTCLR PEAVADLREE DQRVINVLRQ LCSPEALKQN VGFDEANNFD
     SPPRKRFATS SNYPLLSGRS HRNKGCENLY SEKQGFGRYT NCPNRSTDSE QVHDIQCGLW
     QDPYPQFSNQ RYDQVPVNRF SGNYMGGRSF GPNGAGNNFN GSSWNSYGAP NFGGYPYQQQ
     QFTNDRFMQP NQRPSTRPHW GVRY
//