ID   A0A194PQC5_PAPXU        Unreviewed;       718 AA.
AC   A0A194PQC5;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Cryptochrome-1 {ECO:0000313|EMBL:KPI93335.1};
GN   ORFNames=RR46_10595 {ECO:0000313|EMBL:KPI93335.1};
OS   Papilio xuthus (Asian swallowtail butterfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC   Papilionidae; Papilioninae; Papilio.
OX   NCBI_TaxID=66420 {ECO:0000313|EMBL:KPI93335.1, ECO:0000313|Proteomes:UP000053268};
RN   [1] {ECO:0000313|EMBL:KPI93335.1, ECO:0000313|Proteomes:UP000053268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPI93335.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KPI93335.1};
RX   PubMed=26354079; DOI=10.1038/ncomms9212;
RA   Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA   Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA   Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA   Wang W.;
RT   "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL   Nat. Commun. 6:8212-8212(2015).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602081-1};
CC       Note=Binds 1 FAD per subunit. {ECO:0000256|PIRSR:PIRSR602081-1};
CC   -!- SIMILARITY: Belongs to the DNA photolyase class-1 family.
CC       {ECO:0000256|ARBA:ARBA00005862}.
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DR   EMBL; KQ459602; KPI93335.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A194PQC5; -.
DR   STRING; 66420.A0A194PQC5; -.
DR   Proteomes; UP000053268; Unassembled WGS sequence.
DR   Gene3D; 1.25.40.80; -; 1.
DR   Gene3D; 1.10.579.10; DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3; 2.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR   InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR   InterPro; IPR005101; Cryptochr/Photolyase_FAD-bd.
DR   InterPro; IPR002081; Cryptochrome/DNA_photolyase_1.
DR   InterPro; IPR006050; DNA_photolyase_N.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR11455; CRYPTOCHROME; 1.
DR   PANTHER; PTHR11455:SF30; CRYPTOCHROME-1; 1.
DR   Pfam; PF00875; DNA_photolyase; 1.
DR   Pfam; PF03441; FAD_binding_7; 2.
DR   SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1.
DR   SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1.
DR   PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE   3: Inferred from homology;
KW   Chromophore {ECO:0000256|ARBA:ARBA00022991};
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR602081-1};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|PIRSR:PIRSR602081-
KW   1}; Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053268};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          34..163
FT                   /note="Photolyase/cryptochrome alpha/beta"
FT                   /evidence="ECO:0000259|PROSITE:PS51645"
FT   REGION          687..718
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         319..326
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
SQ   SEQUENCE   718 AA;  81434 MW;  732FF3B5AF7A8470 CRC64;
     MSAAGDTLLA ASARAHGLTA PATRAALPTR PPTKHTVHWF RKGLRLHDNP ALREGLVDAT
     TFRCVFIIDP WFASSSNVGI NKWRFLLQCL EDLDSSLRKL NSRLFVVRGQ PADALPKLFR
     EWGTTELTFE EDPEPYGRVR DHNIMTKCRE VGISVVSRVS HTLYKLDKII ERNGGKAPLT
     YHQFQALIAS MPPPPAAEAT ISAQTLSGAT TPITEDHDDR FGVPTLEELG FETENLKPPV
     WIGGESEALA RLERHLERKA WVASFGRPKM TPQSLLASPT GLSPYLRFGC LSTRLFYYQL
     TELYKRVKRV RPPLSLHGQI LWREFFYCAA TRNPNFDRME GNPICVQIPW EKNQDALAKW
     ASGQTGFPWI DSIMIQLREE GWIHHLARHA VACFLTRGDL WISWEEGMKA RISTISNCYS
     TPYLKYIPAL KNMPTRYIHE PWTAPEAVQR SARCVVGRDY PLPMVDHAKA SQLNIERIKQ
     VYALLAKYKP QNLLNPQVVV RPNVMQSSPS PTSIITSINQ SNYLCSQAPE SQSTSPAPSQ
     QFKQANDVFL RPNNTLREAK QPMKQVVIVQ QAQNSNVTPK TTQRSRMQDK FINGQLEISC
     NMDQSKQKNY GLKNLVINNS DPRYNQDVYI QGTHKNIDGL PQTIQMNTFT DNNTKYYVPS
     YNKSDVQVQN THDRNMDTSD QYISNTLDNE SKSNVTDENL SMPTDTVIYP GTENQPEK
//