ID A0A194PY68_PAPXU Unreviewed; 840 AA.
AC A0A194PY68;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 03-MAY-2023, entry version 26.
DE SubName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 {ECO:0000313|EMBL:KPI97694.1};
GN ORFNames=RR46_07441 {ECO:0000313|EMBL:KPI97694.1};
OS Papilio xuthus (Asian swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=66420 {ECO:0000313|EMBL:KPI97694.1, ECO:0000313|Proteomes:UP000053268};
RN [1] {ECO:0000313|EMBL:KPI97694.1, ECO:0000313|Proteomes:UP000053268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPI97694.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPI97694.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
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DR EMBL; KQ459589; KPI97694.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194PY68; -.
DR STRING; 66420.A0A194PY68; -.
DR Proteomes; UP000053268; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08835; ArfGap_ACAP; 1.
DR CDD; cd07603; BAR_ACAPs; 1.
DR CDD; cd13250; PH_ACAP; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045258; ACAP1/2/3-like.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23180:SF399; BLOWN FUSE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR23180; CENTAURIN/ARF; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053268};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 277..371
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 409..535
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REPEAT 685..717
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 718..750
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 531..611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 623..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..558
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..611
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 840 AA; 93873 MW; F08759589C4C5BE5 CRC64;
MKPLIDFDEC LRDSPKFREQ LETEEASIDG LEQKLDKVLK TCSFMIESGK TYMTHRSAFT
NALWDLSSSF SEDPPVMATL NRMIHALQEM NKFHSILLDQ ASRTVLKNLS AFIKIDIKGV
KESKHHFDKI SNDLDIALIR NSQVSRHKSS DVEEAVNLLL ATRSCFRHTA LDHVQKITML
QARKRHEILA TFLSYMQACC TYYHQGADLS EDLEPFLKST ADEVTTMRGD TKSLDKEMEN
RHTIVNSQDT VLPSCKDHAN ETDCKDGLLT SPCLKNLPRM QGYLFKRTSN AFKTWNRRWF
YLYDNRLVYR TGELNVTVME EDLRLCTVKP VLDGERRFCF EVLSPSKSHM LQADSEEMVG
AWIAALQSGI RSAIQQGRGR DPPDSQLVLV PDRDHAHNHP HANDRMKKVR IWEQLLSIPG
NNYCCDCSSP NPRWASINLG ITLCIACSGV HRSLGVHVSK VRSLTLDDWE PDIIKVMAEL
GNKIVNLIYE ANTEGTDLTR PTPNCETSVR EAWIRAKYVS LSFVRNVTAC ERAPPQSPPQ
SPPHSPPHSP PHSPSNSPPP TRAARRWSVR RARRRVRAQP TVPETIADEK SDVNSNTSVS
ESGSKSSGSP VLLIGSELAG ERDIDLSLPS DHDSTEGDDT DELEAEDLSS LSADAVLCRA
ARAHNVCVMR AALAAGASPT ATAPRLRTPL HAAVLSGSVM ACSFLLLNGS KLNAQDEDGK
TPLHLATEAG HTGQVCLLLR YRADQSIKDN EGHTPLDIAV EHANADIVTL LRLTKLNEEM
RENEMSSNDD TYNEVFRDYT QLAHSHPERL VRARHNNNDG NGLQPRKLAI SDKVNYPGES
//
