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Database: UniProt
Entry: A0A194QCV9_PAPXU
LinkDB: A0A194QCV9_PAPXU
Original site: A0A194QCV9_PAPXU 
ID   A0A194QCV9_PAPXU        Unreviewed;       864 AA.
AC   A0A194QCV9;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   12-APR-2017, entry version 4.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=RR46_06534 {ECO:0000313|EMBL:KPJ03378.1};
OS   Papilio xuthus (Asian swallowtail butterfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Lepidoptera; Glossata; Ditrysia;
OC   Papilionoidea; Papilionidae; Papilioninae; Papilio.
OX   NCBI_TaxID=66420 {ECO:0000313|EMBL:KPJ03378.1, ECO:0000313|Proteomes:UP000053268};
RN   [1] {ECO:0000313|EMBL:KPJ03378.1, ECO:0000313|Proteomes:UP000053268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPJ03378.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KPJ03378.1};
RX   PubMed=26354079; DOI=10.1038/ncomms9212;
RA   Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA   Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y.,
RA   Jiang X., Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G.,
RA   Kronforst M.R., Wang W.;
RT   "Outbred genome sequencing and CRISPR/Cas9 gene editing in
RT   butterflies.";
RL   Nat. Commun. 6:8212-8212(2015).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; KQ459185; KPJ03378.1; -; Genomic_DNA.
DR   Proteomes; UP000053268; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053268};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053268};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    441    467       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    479    504       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    574    595       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    602    625       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    637    656       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    677    695       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    788    809       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED      138    172       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   864 AA;  98615 MW;  FDC4D19952B67C02 CRC64;
     MAGTMSCYLA RPPYAAVPER LTPAQPRCGK GQVRTQVELT IYDAGYTMGS MFRSEEMVLC
     QLFVQPEAAY ISMYELGEAG IAQFRDLNPH VNDFQRRYVS EVRRCSEMER KLRYVRGELP
     EPPPPPKPSP TVLSPREINI LEERIDYVES EIQEITRNAQ NLKTDYLSLK ELKLLIEKTQ
     TFFQDHSHHR KISASVQVYN NEGVLGHLGF IAGVVATPKV PSFERMLWRI SHGNIFFKQA
     QIDEPLKDPV TGHELQKTVF VVFFHGEQIK LRVKKVCNGF QATLYHCPAT YKEQQEMLAG
     VDSRIKDLEI VLEQTEQHRR LVLANIARDL STWLVAVRRE QAIYHTLNMF SMDIVKKCLI
     AECWVPRTDL PILQKALDNG VKASGSPIPS FLHHVPTHET PPTFNRVNKF TSGFQNLIDS
     YGVASYREVN PALYTIITFP FLFAVMFGDV GHGLIMTAFA AIIIILEKRL AKKKTDNEIW
     NIFFGGRYII LLMGIFSIYT GLIYNDMFSK SLNIFGSSWR NTYDNETLVR HRMLELDPAI
     AYTQTPYPFG LDPAWQFAAN NIIFLNSFKM KLSIIFGVIH MAFGVTMSVV NFNFFKKNYM
     IYLQYIPQIL FLLLLFWYLC ILMFMKWTMY SAVSPDPAYG TYCAPSVLII FINMMLMKKS
     DSRPPCPQNM YAGQEPLQKT FLAVAFLCVP IMLFGKPVYQ MIADKKKKQY QQGVESGDVV
     EKDPHDGGMG EVLITQAIHT IEYVLGTVSH TASYLRLWAL SLAHAQLSAV LWQRVLRIGL
     GGGSPINAIL LYVIFAVWAF FTLAILVLME GLSAFLHTLR LHWVEFMSKF YEGQGYAFVP
     FSFAAILERE DDDLVVQKNG AAQE
//
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