ID   A0A194QR32_PAPMA        Unreviewed;       489 AA.
AC   A0A194QR32;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Set1/Ash2 histone methyltransferase complex subunit ASH2 {ECO:0000313|EMBL:KPJ05991.1};
GN   ORFNames=RR48_14433 {ECO:0000313|EMBL:KPJ05991.1};
OS   Papilio machaon (Old World swallowtail butterfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC   Papilionidae; Papilioninae; Papilio.
OX   NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ05991.1, ECO:0000313|Proteomes:UP000053240};
RN   [1] {ECO:0000313|EMBL:KPJ05991.1, ECO:0000313|Proteomes:UP000053240}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ05991.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KPJ05991.1};
RX   PubMed=26354079; DOI=10.1038/ncomms9212;
RA   Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA   Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA   Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA   Wang W.;
RT   "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL   Nat. Commun. 6:8212-8212(2015).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; KQ461198; KPJ05991.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A194QR32; -.
DR   STRING; 76193.A0A194QR32; -.
DR   InParanoid; A0A194QR32; -.
DR   Proteomes; UP000053240; Unassembled WGS sequence.
DR   GO; GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd12872; SPRY_Ash2; 1.
DR   Gene3D; 2.60.120.920; -; 2.
DR   InterPro; IPR037353; ASH2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR10598; SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2; 1.
DR   PANTHER; PTHR10598:SF0; SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:KPJ05991.1};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053240};
KW   Transferase {ECO:0000313|EMBL:KPJ05991.1}.
FT   DOMAIN          245..444
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   REGION          65..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   489 AA;  55302 MW;  1C80C23E36665924 CRC64;
     MATAGCAAIA RRPATLDFRS PRRTRAPYSL PGDHTDALPP RFLHRLLPYT TLNFMAVPLA
     GNVKGRQGKR RPAVGGLETG APVGKKGRAS DLSALKLPSH GYPTEHPFNK DGYRYILAEP
     DPQAPFRQEF DENNEWSGKP IPGWLYRALC PGAVLLALHD RAPQLRLSED RLAVTGDKGY
     CMVRATHGMY VLQHLDKNEW NSKRNERKCK NDRVSIPLTR TATGTSSLNP TPKRRLDRCE
     FDENNEWSAA SRPGWLYRAL CPGAVLLALH DRAPQLRLSE DRLAVTGDKG YCMVRATHGV
     SRGAWYWEAV VEELPEGAAA RLGWGRRYAN LQAPLGYDKF GYSWRSRKGT RYIHTTDKTS
     KLKKKKRSTE PLVKFKSHLY YEDKDNIQES LNNLKPLSGS RILFFKNGEC QGEAFTDIYQ
     GCYYPTVSLH KNITVSVNFG PNFKFPPATE YNYRPMSEKA EEAICEQTMA DLLYLTENEG
     KLRLDNFNL
//