ID A0A194QRP6_PAPMA Unreviewed; 724 AA.
AC A0A194QRP6;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN ORFNames=RR48_12901 {ECO:0000313|EMBL:KPJ08162.1};
OS Papilio machaon (Old World swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ08162.1, ECO:0000313|Proteomes:UP000053240};
RN [1] {ECO:0000313|EMBL:KPJ08162.1, ECO:0000313|Proteomes:UP000053240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ08162.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ08162.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000256|ARBA:ARBA00005783,
CC ECO:0000256|RuleBase:RU365057}.
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DR EMBL; KQ461155; KPJ08162.1; -; Genomic_DNA.
DR RefSeq; XP_014367549.1; XM_014512063.1.
DR AlphaFoldDB; A0A194QRP6; -.
DR STRING; 76193.A0A194QRP6; -.
DR GeneID; 106718068; -.
DR KEGG; pmac:106718068; -.
DR InParanoid; A0A194QRP6; -.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000053240; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR048292; SDA1_C.
DR InterPro; IPR007949; SDA1_MD.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF21638; SDA1_C; 1.
DR Pfam; PF05285; SDA1_dom; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365057};
KW Reference proteome {ECO:0000313|Proteomes:UP000053240};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 61..423
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT DOMAIN 507..660
FT /note="SDA1 middle"
FT /evidence="ECO:0000259|Pfam:PF05285"
FT DOMAIN 678..723
FT /note="SDA1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21638"
FT REGION 229..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..536
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..688
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 689..704
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 724 AA; 84400 MW; 92C5119B38FB916D CRC64;
MVRHNNQLPN NLTQLQNLIK RDPESYKDEF RQQLAHFETT LEIFNLNPTQ YNKKLDEQAM
FLAQVTQCYL SDMKTFPQKI VDILKTHNTI LHSDMRLSLC KCLILLRNKN FVTAYDLLEL
FFTLIKCQDK NLREYLKTHI ITDIKNMNMK HKDMKLNSTL QNFIFSMLRE SNAKTAKLAV
DILIELYHKN IWNDHKTVNI IADIGCFSKI TKVMVASLKF FLSRDEEEKE ENSDSEDEID
PRDTMISNKF NKKTRKREKM VDKVKKIAKK MKRKKEKAPI FNFSALHLIN NPQGFAEKLF
KQLESSNERF EVKLMSLDVI SRLIGLHNLF LFNYYPFIAR LIMPHQREVT RILQFAAQAS
HELVPPEVLE PVMKAIANNF ITERNSTDVM AVGLNAVREI CARCPLAVGE DLLRDLVQYK
TYKEKSVMMA ARSLIQLYRQ NMPNLLHKKD RGRPTEALAE LKSKQYGEMD IKSYIPGSEV
LLEKKEVKAV ENKKKPRKKG EDSDDEWVDI ASSDSEIDIS DSDEDGNDDE DETKSNSTDG
EDGSVNDDSI NNELNSKGNI KDSDENRKIL KAKRKDTKQD MSEKIETARN IAMDTIFTDE
DFKRIEAAQI KKCVSGVKRN KSTIEEPEES TELVQLSAIE NIHKKRKHDK NARLESVHKG
REERDKYGYK DRRKNANCSK TNREKRKTKA YQMVKHKAKG KVKRSFKEKQ IAFRNYLIKQ
KKMK
//
