ID A0A194QZZ0_PAPMA Unreviewed; 801 AA.
AC A0A194QZZ0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cyclic nucleotide-gated cation channel {ECO:0000313|EMBL:KPJ09161.1};
GN ORFNames=RR48_15302 {ECO:0000313|EMBL:KPJ09161.1};
OS Papilio machaon (Old World swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ09161.1, ECO:0000313|Proteomes:UP000053240};
RN [1] {ECO:0000313|EMBL:KPJ09161.1, ECO:0000313|Proteomes:UP000053240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ09161.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ09161.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KQ461108; KPJ09161.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194QZZ0; -.
DR STRING; 76193.A0A194QZZ0; -.
DR InParanoid; A0A194QZZ0; -.
DR Proteomes; UP000053240; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:UniProt.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.5.300; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR032406; CLZ_dom.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF16526; CLZ; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053240};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 207..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 525..631
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 41..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..736
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..762
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 660..712
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 801 AA; 91131 MW; 1AB8F9140CCCEF48 CRC64;
MWAYIIAAAR GDSRQTVNKN NSMQNNSDDH LFSYRDGKVF TLSSSGGPRP GPSGLTSRDM
IKTPRFPHFK KTLSTNTLNP LHMQANCRNE LEDGIGPFEE VVSDVGPRSS WMQRQVSRFA
RNLRYRITGE GRTKPPDWFL DKFAAQTFSD PDEPLYQTKR SKLLCGLRLA FDPTLPSHYH
ATGQDACWST DVATSDTHLL CTNELQWLAV VSLAILYNVV FVIGRAVFWE LDNLTVLWFI
LDYLCDAIYL IDTVIHVHEG YLEQGLMVKD STMLRKHYLK SDSWRYDLIS LIPTDIAYYW
WKPGTCDYQR LPCPVIVRLN RLFRLPRMWE WFDRTETATS YPNAFRICKV VMAILVLIHW
NACLYFAISY AIGFGTDNWV YNLTGSRNES LAHQYIYSFY WSTLTLTTIG ETPQPEIDAE
YLFVVADFLA GVLIFATFVG NIGSMISNMN VARVEFQNKM DGVKQYMAFR KVSGELEARV
IRWFAYTWAQ SGALDEENVL SSLPDKLKAE IAIRVHLDTL RKVRIFQDCE PGLLEALVLK
LRLQVFSPGD YICRKGDVGK EMYIVKRGRL QVVADDGKTV LATLSAGSVF GEVSVLEIAG
NRTGNRRTAN VRALGYSDLF CLAKRDLWEA LADYPDARAT LTERGCQLLR KDGLLDETVF
ENAQTTQQSL EETVHKLETT VEMLNNRLQG LLADVGEEQA KIKQRINKLE VRIIESDDEE
TDSEDTSADG SDLRSDIVQV YDSSSGPPIS SPRSTTMFMN NPVRERGYSL SVERTPGLMH
FPPEPRSKSL RIKKIHKDIS K
//
