ID A0A194RID5_PAPMA Unreviewed; 882 AA.
AC A0A194RID5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 28-JUN-2023, entry version 25.
DE SubName: Full=Potassium voltage-gated channel protein eag {ECO:0000313|EMBL:KPJ17322.1};
GN ORFNames=RR48_08813 {ECO:0000313|EMBL:KPJ17322.1};
OS Papilio machaon (Old World swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ17322.1, ECO:0000313|Proteomes:UP000053240};
RN [1] {ECO:0000313|EMBL:KPJ17322.1, ECO:0000313|Proteomes:UP000053240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ17322.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ17322.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KQ460154; KPJ17322.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194RID5; -.
DR STRING; 76193.A0A194RID5; -.
DR InParanoid; A0A194RID5; -.
DR Proteomes; UP000053240; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.1200.260; -; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003949; K_chnl_volt-dep_EAG.
DR InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR10217:SF435; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN EAG; 1.
DR PANTHER; PTHR10217; VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01463; EAGCHANLFMLY.
DR PRINTS; PR01464; EAGCHANNEL.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053240};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 61..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 395..495
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 565..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 720..762
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..882
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 765..799
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 736..760
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..822
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 882 AA; 95375 MW; E001385FF3069BAF CRC64;
MSSALAPLPS AVLGMTSVCC CAARGVWQVL SLSGDVLPQY RQEAPKTPPH ILLHYCAFKA
IWDWIILCLT FYTAIMVPYN VAFKNKTSED VSLLVIDSIV DVVFFIDIVL NFHTTFVGPG
GEVVSDPKVI RKNYFKSWFL IDLLSCLPYD VFNAFDHDED GIGSLFSALK VVRLLRLGRV
VRKLDRYLEY GAAMLILLLC FYMLVAHWLA CVWYSIGRSD ADSGLQYSWL WKLANVTQSP
YSYVWSNESD GPELVNGPSR KTMYVTALYF TMTCMTSVGF GNVAAETDNE KIFTICMMIV
AALLYATIFG HVTTIIQQMT SATAKYHDML NNVREFMKLH EVPKALSERV MDYVVSTWAM
TKGLDTDKVL NYCPKDMKAD ICVHLNRKVF NEHPAFRLAS DGCLRALAMH FHMSHSAPGD
LLYHTGESID SLCFIVTGSL EVIQDDEVVA ILGKGDVFGD SFWKDTAVGQ SAANVRALTY
CDLHTIKRDR LLEVLDFYQA FANSFARNLT LTYNLRHRLI FRKVADVRRE RELMERRKRE
PQLEQAQDHL VRKIFSRFRR ERSVAAAPGP RASAAPTGAP APAAPAAPTA PTAPTDAANT
PCGDAERGEG AAGPGPGRGG AGPGTARGKW GRLLAGGSLD APDAPRAAFT RSLSARDRPP
ADASAAAPAL APTSLKQASL RENLNTDIVA GAAVAAVVVS LLRSAAAALP ACSALPWRAA
TPSTRRRTTS ALSPVRSPRP PHPRAPTAPA APPAPPTPAV PAAHEAALAE LRRDVRNEVQ
RLQQKLGRVE DLLTFLAAKL GADPPPPAST APPVPAAPPV PAAVTSAPSA SSDTSATAAA
RKRRSKARSK GAAPQVPTPT SPSEPPNSPG AAGAAGRRRE FV
//
