ID   A0A194RKT8_PAPMA        Unreviewed;      1668 AA.
AC   A0A194RKT8;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Adenylate cyclase type 10 {ECO:0000313|EMBL:KPJ17945.1};
GN   ORFNames=RR48_07342 {ECO:0000313|EMBL:KPJ17945.1};
OS   Papilio machaon (Old World swallowtail butterfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC   Papilionidae; Papilioninae; Papilio.
OX   NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ17945.1, ECO:0000313|Proteomes:UP000053240};
RN   [1] {ECO:0000313|EMBL:KPJ17945.1, ECO:0000313|Proteomes:UP000053240}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ17945.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KPJ17945.1};
RX   PubMed=26354079; DOI=10.1038/ncomms9212;
RA   Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA   Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA   Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA   Wang W.;
RT   "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL   Nat. Commun. 6:8212-8212(2015).
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DR   EMBL; KQ460075; KPJ17945.1; -; Genomic_DNA.
DR   InParanoid; A0A194RKT8; -.
DR   Proteomes; UP000053240; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 2.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF00211; Guanylate_cyc; 2.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 2.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053240}.
FT   DOMAIN          84..220
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   DOMAIN          410..484
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1049..1071
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1097..1123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1108..1123
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1668 AA;  189826 MW;  9BE33188B3F041F9 CRC64;
     MSHADNDLLE EDSTDEDSPK TANLSDLTHE FFGRESLSEE QIDQDVEVRL SRKQTLILAT
     MVPDEILLLE NFDEKREPKR FVGVLLMADV SGYTALSERY TNSGKGGTYR LTVTLNTYLG
     SLIEVIYSHG GDIIKFAGDA FLALWKTDKR SYLSHTIHTA IACALIIQHS FGSYETDVKV
     NLKVKLAISA GNLLFAPIGK GIDMNYIIFG LPVLEAKTAE SLCLSGEVKL TPTAWGHCYS
     RNYDYVIHDD GHVTIKSILY DPREKDVTKP FLGFSGMLRQ IKKPLIGIEN LPENLLDVTK
     TKIGWESLKT NEALNVRKTI LIAEERNIGS EIRKFMIRPV LTQIDAHQPL EYLTEMRHVS
     VLFITLKPRN CPFPQLITIV NNSYQITCEI VYKSMGCVNK IILFDKDIMI LVVFGLRGFK
     HESEAQAALK CASGIKKSLS ALDGVLEVSI GVTTGQVYCG VIGHPLRREF TIIGAVVNKA
     ARFMCYFRNK ITCDETTFVK SKMSSNGFTL QPAAELKGIN HPGKIFEYTE EIRVKELYDI
     PVLPPLLNRS DEFEYFQNWI DNSHLSFRDF DALLFIGEYC SGKTRLLEWL TRYVRNKGLR
     TCYLSLSSIH SATPYLALGQ IVNEMLGLKE PITGFSKEEK IVQMLNSYNS DLCYLNNIIK
     VRFAYHEGIY TQDENVRKEK AKTIFMKLIR SFPEPHVIFL DDLQNLDASS WEFISIMLDS
     PKIYTVLTIT RGKFNSIQNW IYNVLINSSI RKIVLGPLSS QWIPALACQI LDVEAVPKDL
     CDTLKTKCKG LPGLVESFIV NLFSNGALET KRIHKHELDN LKNEDLQFPD AELLRLQAVS
     VDDQKALDQF IADNSTEDIA VCIVTKKEQL NTDINEQNVD AIIMVQIDSL TPYQQLLLKI
     ASVIGNVLSR TLLENIMYEN NPLTTAKAIK RLFAMRILTC ANIRYRLNRR VTNATSVTSV
     TINANLSCDC SFDYDPEEYE NLPKYAFCKV MKFRNKNSRK TCYELLPMNQ KKEFHSRIVS
     YLEKTKQKCP DCGGIIMIVQ SVTNVSNHSY ETRRSSNKID QARDSDTSLP QIGEEIEVSS
     IDISQNVSSM NNRSAIEIRR TKSDSSSRQA LEPKSTLSDK NTRLSLKQTD KPSTILKNKN
     ERLDIIDGNR RSMKRVTMTS LLSKDISFNE MNNSKIFDML RAVTEASTIS EWHELGVVDS
     CDDVNENGKG YFKLKIERGV SKTRFEKCAC LELNITIYEQ LINHAREADL KVKMIEFLIN
     YSYFNLLANN FECIYPKLDE AEDICFEKVV ENMTSFDKRR FLGRIHSLRA AALLMSGKLA
     AAKIHIERAT KIYGFNLDKV SDFFNIRNII TATPFKRSKY LKHSMILKSD SIFCLNVITL
     LFSALGDDNI SRVSALRALN LTQKVKCNII DLCDAFSNAI QVELVRGNAE FTKDIERMAI
     LTFKNLSQPI QAEEMFAIGK FFMASFRGRL ARGKLAEAIR SGFRSLVISR FLHADTISLD
     MIPDLFYILL SRRRIEEAID ILKLSFEFSY KQSTTEWETW YYALCMDLIL DAGFQLETPN
     EISRYAEHAL NTGLPAGLSR RRLIVGLWTY WLRADVDRKA KRFEAEALNW TAYEEDDGSL
     NTLLSAMRLA EGMLESLARK MDDLRKASLE TCILNYSVKF VICVKFYL
//