ID A0A194S8I4_RHOGW Unreviewed; 554 AA.
AC A0A194S8I4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=histone deacetylase {ECO:0000256|ARBA:ARBA00012111};
DE EC=3.5.1.98 {ECO:0000256|ARBA:ARBA00012111};
GN ORFNames=RHOBADRAFT_52750 {ECO:0000313|EMBL:KPV75716.1};
OS Rhodotorula graminis (strain WP1).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=578459 {ECO:0000313|EMBL:KPV75716.1, ECO:0000313|Proteomes:UP000053890};
RN [1] {ECO:0000313|EMBL:KPV75716.1, ECO:0000313|Proteomes:UP000053890}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WP1 {ECO:0000313|EMBL:KPV75716.1,
RC ECO:0000313|Proteomes:UP000053890};
RX PubMed=26441909; DOI=10.3389/fmicb.2015.00978;
RA Firrincieli A., Otillar R., Salamov A., Schmutz J., Khan Z., Redman R.S.,
RA Fleck N.D., Lindquist E., Grigoriev I.V., Doty S.L.;
RT "Genome sequence of the plant growth promoting endophytic yeast Rhodotorula
RT graminis WP1.";
RL Front. Microbiol. 6:978-978(2015).
CC -!- SIMILARITY: Belongs to the histone deacetylase family. HD type 1
CC subfamily. {ECO:0000256|ARBA:ARBA00006457}.
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DR EMBL; KQ474077; KPV75716.1; -; Genomic_DNA.
DR RefSeq; XP_018271765.1; XM_018416491.1.
DR AlphaFoldDB; A0A194S8I4; -.
DR STRING; 578459.A0A194S8I4; -.
DR GeneID; 28976939; -.
DR OMA; FHSEEYM; -.
DR OrthoDB; 1327607at2759; -.
DR Proteomes; UP000053890; Unassembled WGS sequence.
DR GO; GO:0004407; F:histone deacetylase activity; IEA:UniProtKB-EC.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 2.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR003084; His_deacetylse_1.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF25; HISTONE DEACETYLASE 3; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 2.
DR PRINTS; PR01270; HDASUPER.
DR PRINTS; PR01271; HISDACETLASE.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Reference proteome {ECO:0000313|Proteomes:UP000053890}.
FT DOMAIN 85..252
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT DOMAIN 254..350
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 434..554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..474
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 554 AA; 59440 MW; B44F19E411132142 CRC64;
MVALHPPPPF SMNHPAFSSA AFLQGPSTST VVQEYGVESA AGGNGDASAA QLEGESWRGG
FSGGSAVGVH SAPRVSYYFP QGERHPMKPH RLTLTNHLVL GYGLHKRMDV FQPRSATKEE
LEAFHDEDYV DFLARVTPDN VRHFTSVLSR FNIGDDCPIF SDMYSYCRQY AGASLMAARK
IVSGSTDIAV NWTGGLHHAK KSEASGFCYV NDIVLAILEL LRTHARVLYI DIDIHHGDGV
QEAFYNTNRV LTNFSLNVPL QDGIDNESYV ALFKAIMEPT IHTFRPDAIV LQCGADSLGC
DRLGCFNLSI AAHGECVRFI KSFALPLVVL GGGGYTIKNV SRCWAYETAV CLGVEQDLPN
ALPHTAYDDF FAPDWKLHPE LASGRNRLEN LNSRRQLERI RVACLERLRY MHGAPSVQMH
EVPPSLAQWL ADEDGRDEQR ERDEDGAHAP DGRSDAHRAA NDYFSHDGDR EGDAVGGRTS
SSGLAGGSGA PPPTPAATSS TTTTTAGASL ATTAGSKKRR KVAAAGAAGG AGSSAAGGGV
KPVRIEAGGA EDEA
//
