ID   A0A199NTQ6_9MICC        Unreviewed;       359 AA.
AC   A0A199NTQ6;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=DUF218 domain-containing protein {ECO:0000259|Pfam:PF02698};
GN   ORFNames=AN277_0203475 {ECO:0000313|EMBL:OAX52469.1};
OS   Rothia kristinae.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Rothia.
OX   NCBI_TaxID=37923 {ECO:0000313|EMBL:OAX52469.1, ECO:0000313|Proteomes:UP000053171};
RN   [1] {ECO:0000313|Proteomes:UP000053171}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RuSp02-3 {ECO:0000313|Proteomes:UP000053171};
RA   Waterworth S., Matcher G.;
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:OAX52469.1, ECO:0000313|Proteomes:UP000053171}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RuSp02-3 {ECO:0000313|Proteomes:UP000053171};
RA   Waterworth S.C., Walmsley T.A., Matongo T., Davies-Coleman M.T.,
RA   Dorrington R.A.;
RT   "Identification of putative biosynthetic pathways for the production of
RT   bioactive secondary metabolites by the marine actinomycete Kocuria
RT   kristinae RUTW2-3.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAX52469.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LJBJ02000004; OAX52469.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A199NTQ6; -.
DR   Proteomes; UP000053171; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd06259; YdcF-like; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR003848; DUF218.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR30336; INNER MEMBRANE PROTEIN, PROBABLE PERMEASE; 1.
DR   PANTHER; PTHR30336:SF18; MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF02698; DUF218; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053171};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        37..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        71..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        110..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        141..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          182..326
FT                   /note="DUF218"
FT                   /evidence="ECO:0000259|Pfam:PF02698"
SQ   SEQUENCE   359 AA;  38752 MW;  46EFE567C61BAE6B CRC64;
     MRDILQDPAV DGVLHLAIAL GVVVYCLVGF RRAGHRLRYG IILPIGVVLL IGAVLRLAGS
     ARVPWADVVG GVIALLVFLG LCLGYLVLTV FLLVNGVTIM RKEGRRPATL LSFAAGAWMV
     LLPALPVVLA ATGALRQDAV LVVFAAIYSV LFAATAYVAF FFLGFLTSAV GYRKLARRFA
     PDAIIVLGAG LKGEEPTPLL AGRLDRGLEV YHRETARGRA PVMIPSGGQG PDEVIPEGEA
     MRRYLADRGV PAEHLRPETR STTTLENLLF SRELLEDPDR PVVVATSDYH VYRAAMLLRK
     AGLRGRAVGS RTAGYYVPSA FLREYAAVLV TNRWAHLLAF APIVAMILAF YGVVLTQVV
//