ID A0A1A6C8F1_9GAMM Unreviewed; 582 AA.
AC A0A1A6C8F1;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Thpro_020540 {ECO:0000313|EMBL:OBS10824.1};
OS Acidihalobacter prosperus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Acidihalobacter.
OX NCBI_TaxID=160660 {ECO:0000313|EMBL:OBS10824.1, ECO:0000313|Proteomes:UP000029273};
RN [1] {ECO:0000313|EMBL:OBS10824.1, ECO:0000313|Proteomes:UP000029273}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5130 {ECO:0000313|EMBL:OBS10824.1,
RC ECO:0000313|Proteomes:UP000029273};
RX PubMed=25342676;
RA Ossandon F.J., Cardenas J.P., Corbett M., Quatrini R., Holmes D.S.,
RA Watkin E.;
RT "Draft Genome Sequence of the Iron-Oxidizing, Acidophilic, and Halotolerant
RT 'Thiobacillus prosperus' Type Strain DSM 5130.";
RL Genome Announc. 2:0-0(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS10824.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JQSG02000001; OBS10824.1; -; Genomic_DNA.
DR RefSeq; WP_065089177.1; NZ_JQSG02000001.1.
DR AlphaFoldDB; A0A1A6C8F1; -.
DR OrthoDB; 6017161at2; -.
DR Proteomes; UP000029273; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000029273};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 222..274
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 356..576
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 582 AA; 63048 MW; 9F3083798F510E96 CRC64;
MAGIALARRH RRHAALAGML VVALTLFALL GHASGQPLWV NTVLMSHNAD GVPGPMSIQS
ALFFLIMGLA LSLQGQTLRA ASRIVDACVG ILLIMALTIL AGYLFNASAF FGQSAAIRTS
PQTLLCMTLL VFSLFERRTR NGIYAVLVAP GIGSQFARMA LPFVLVVPLL IITAGTYLTA
SGWQSDAYST ATMAVVLAAA LMVFVMLAAA KINQTAATLT DTESQLRLLL DSAGEGIYGL
DREGRTSFVN PATCDMLGFT AEELLCQPFH ELVHHHRSDG SSYPLAECPM SKALEDGQVH
RVGNEMFWRK DGSSFPVDYV TTPIRKEGVL MGAVVIFNDV TERVRNERMK DEFVAVVSHE
LRTPLTSIKG ALGLLASGRL GTLTQDGKDM ANIAYDNTQR LELLVNDLLD INKIQLAETQ
FQMHAVDLHA LIVKALDANR PYAEKFAVEF AWLPATEDGI YVRGDEHRLI QVMSNLLSNA
VKYSPRGSRV NVSTQCVDHT VRVSVRDHGP GVPLGYRPHI FEKFSQADSS ETRARGGTGL
GLAISKAIVE KHGGNIGFES TPGQGATFHF DLPLSDVTRK TA
//
