ID A0A1B6PC15_SORBI Unreviewed; 467 AA.
AC A0A1B6PC15;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Dehydrogenase E1 component domain-containing protein {ECO:0000259|Pfam:PF00676};
GN ORFNames=SORBI_3008G062200 {ECO:0000313|EMBL:KXG23147.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:KXG23147.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:KXG23147.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
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DR EMBL; CM000767; KXG23147.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B6PC15; -.
DR EnsemblPlants; KXG23147; KXG23147; SORBI_3008G062200.
DR Gramene; KXG23147; KXG23147; SORBI_3008G062200.
DR Proteomes; UP000000768; Chromosome 8.
DR ExpressionAtlas; A0A1B6PC15; baseline and differential.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR43380; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43380:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768}.
FT DOMAIN 170..453
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 467 AA; 51866 MW; FA5947C71C200ECB CRC64;
MPACHHWRGL ELGRAEHGVS DMAALWLSRA STQLARRAAR RLPAGRGSGE PTTSPWFLGA
VPPPALGSTA AVETSRRRGF CSVRRFAGES SAAAATVVDE EPENGFVASD QQAVHFPGGK
VSFVAEMNFL PDSMKERINC YRVLDDDGRT ISGSRFQEVS KELAVKMYSE MVTLQIMDTI
FYEAQRQGRI SFYLTSNGEE AINIASAAAL SMDDIVLPQY REPGVLLWRG FTLQEFANQC
FGNKLDYGKG RQMPIHYGSN RLNYFTVSSP IATQLPHAVG AAYSLKMDKK DACAITYFGD
GGTSEGDFHA ALNFAAVMEA PVIFFCRNNG WAISTPTTEQ FRSDGVVIRG QAYGIRGIRV
DGNDALAVYS AVHAAREMAI TEGRPILVEA LTYRVGHHST SDDSTKYRPV DEIEHWRTAR
DPISRYRKWV QGNDWWSDAE ESELRSRVRK EVLNKDSSFQ HTVIHRT
//
