ID A0CHP5_PARTE Unreviewed; 929 AA.
AC A0CHP5;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Chromosome undetermined scaffold_183, whole genome shotgun sequence {ECO:0000313|EMBL:CAK70312.1};
GN ORFNames=GSPATT00038414001 {ECO:0000313|EMBL:CAK70312.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK70312.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK70312.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK70312.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
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DR EMBL; CT868078; CAK70312.1; -; Genomic_DNA.
DR RefSeq; XP_001437709.1; XM_001437672.1.
DR AlphaFoldDB; A0CHP5; -.
DR STRING; 5888.A0CHP5; -.
DR EnsemblProtists; CAK70312; CAK70312; GSPATT00038414001.
DR GeneID; 5023494; -.
DR KEGG; ptm:GSPATT00038414001; -.
DR eggNOG; KOG3518; Eukaryota.
DR HOGENOM; CLU_010133_0_0_1; -.
DR InParanoid; A0CHP5; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR12673; FACIOGENITAL DYSPLASIA PROTEIN; 1.
DR PANTHER; PTHR12673:SF159; RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR JJ; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000600}.
FT DOMAIN 69..248
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 592..929
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
SQ SEQUENCE 929 AA; 109694 MW; 9DA8C659A7C258C1 CRC64;
MRVGGNGALD TSVTKTKKKE TYNSQIDHSY KPKQQMTQAN IQKRKDLAAK KIFRFLYRIY
KQKEKQHRYR KFIIEELINT ERNYVHDLRI LIVIQSQVKQ WLNKQQIEII FNNLQQLYDL
NNPFLQDLEG FLPYKRFKLL GPIIKGLAPF FKVYFTFYEG FNKSMATLKQ CISQKEDLRK
FLKNMTEQKE YHHQDIESYL IKPVQRIPKY NLLLEDLIKH TEKAHPDYQN LCDCLDLFKK
INDDNNKNME QFLSSKLFDL EKWFGSKLNQ KLVNSKRKYI TELLTTILDQ NNRVINVTAF
ILSDLIIIAE RQLHQYQYVQ SVFLDEQSGC LDVENQQHLQ NIYILQGMNG QSITFIEQTP
NDKIEKMAKL LKIIQECKEK SKYTFQRLAS RQGSEIKVQL NKIKVTALGL DERQENLSSY
KVYIIEVGID EVFQKLFLRF SQCIKIQDYI KKKYPTIQLH FLKQSTTLSL LNDQKEIESR
MIAIPLFVSS LLMSELARQD PQILKDLGLP ENFYELPSQA DKFRNQRNGT QKGPDRFSYV
SPTRTLIKTV DYGNDQHSIQ NNQCNRRLLS ASSMISRNIT LVEEKKKKKE KDVIQILVNH
AIPKEKPWEF NIQNNTKVLH VLDQIQKIME LQQIYDFKLY IYDNKSRVKI LQNDENICDL
FGDSFIFAKK KKELWFKKFL YLDLEYEKTL LYSDATRMKL LYYQLVKDIQ ISTFPFPTQN
QYIKLAAIHL YLQNCNLSYD IIQQIVPSAI LQLKQREYWN CVVTQEFKEF KASIDNTQST
MVEISEPEEI AKVKSKGIFS SFTQSVQTQF SQIENINIDL TKAMIQFISE CLRNDFCIQQ
LFQVVCKEAL SQFGEQNLVL GVSYHGIRLY SSSKDRIWEK IEQPQSFNVF PGSIEIGFKG
RKLKFETNQG FQIQSLFDEY QALKSSNQE
//
