ID A0CX44_PARTE Unreviewed; 3036 AA.
AC A0CX44;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Chromosome undetermined scaffold_3, whole genome shotgun sequence {ECO:0000313|EMBL:CAK75361.1};
GN ORFNames=GSPATT00001565001 {ECO:0000313|EMBL:CAK75361.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK75361.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK75361.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK75361.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
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DR EMBL; CT868207; CAK75361.1; -; Genomic_DNA.
DR RefSeq; XP_001442758.1; XM_001442721.1.
DR STRING; 5888.A0CX44; -.
DR TCDB; 1.A.3.2.4; the ryanodine-inositol 1,4,5-triphosphate receptor ca(2+) channel (rir-cac) family.
DR EnsemblProtists; CAK75361; CAK75361; GSPATT00001565001.
DR GeneID; 5028543; -.
DR KEGG; ptm:GSPATT00001565001; -.
DR eggNOG; KOG2243; Eukaryota.
DR eggNOG; KOG3533; Eukaryota.
DR HOGENOM; CLU_000207_0_0_1; -.
DR InParanoid; A0CX44; -.
DR OMA; LECNINS; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0006816; P:calcium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 2.80.10.50; -; 2.
DR InterPro; IPR014821; Ins145_P3_rcpt.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR036300; MIR_dom_sf.
DR InterPro; IPR016093; MIR_motif.
DR InterPro; IPR013662; RIH_assoc-dom.
DR InterPro; IPR015925; Ryanodine_IP3_receptor.
DR InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR PANTHER; PTHR13715:SF99; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR; 1.
DR PANTHER; PTHR13715; RYANODINE RECEPTOR AND IP3 RECEPTOR; 1.
DR Pfam; PF08709; Ins145_P3_rec; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF02815; MIR; 1.
DR Pfam; PF08454; RIH_assoc; 1.
DR SUPFAM; SSF100909; IP3 receptor type 1 binding core, domain 2; 1.
DR SUPFAM; SSF82109; MIR domain; 1.
DR PROSITE; PS50919; MIR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2400..2417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2601..2621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2659..2680
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2687..2708
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2728..2753
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2774..2794
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2877..2898
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 382..430
FT /note="MIR"
FT /evidence="ECO:0000259|PROSITE:PS50919"
FT REGION 736..817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1887..1908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1171..1209
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2481..2515
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3002..3032
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 736..778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..817
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3036 AA; 357633 MW; 6EFE3D75AB76D592 CRC64;
MSQPITYSSL ISLSLAKFPQ VYMYTDGFMS NDFELISFNS VHGNLFHDFQ NTVFRIIPVL
NFKWTQKLLK EIVQEDFQKL SEIQVVKQRK GQIQSLRTNL DGEVTSNISL TSKLTGVPLI
FGSSTFMLVH VTSLKFLTLN DENPEDLHFQ LKDFPEEGSI MKFTPCLNFQ KLRTNIVYNK
DAVILSSTKV VCNRPPSLYT FYKGQEYKYK ESKDKQLKKQ FQQEVKRSKI IGSIEYQTRW
RVEGYHCASN NEKQSEFDDY LHVGDVIALY LSELKLHVNA LKPYDPFKKI LQILKIENLT
SAEPQTKQKD QLLKLTKTQQ HLDKEFNLNQ SDAKILKKIL IEDVVVTFQN FNYFNSTESQ
KKLLDLPNSC FWKIESADQM SGGRVDWNKI YRLRHYQTGR YLQITKNGNL VDMELISEPN
QNALFKFSQI QNSEDSEVTY IKRDSFYYLL HIETGQYLGI SDEVNEVNPK IEQLSKEAEV
EVKQAYLSVV QNHYTTFRVK KIDFSDMWET YMLQYSLPFF LEAIDYIQRL HQKHIVNSTI
AYNDEDIKSK LHFYQIFLKL DRMLDMYCEF VNNKLISNIS AKQEYSYIVT NRQNVVREQN
IFILLVWMLF RCFPSRQIIE KYPQKFEAMK IDFMDEKDFI FRVQSFLQSN TLKHHPRMLV
KLEDGHNKRQ IYLSYKVYMT IKDFCKDNKS NQRTLMKLLN IFYNHIGLGD QIVDTLANSI
SKTKSILQQL PKTMISMPQK PNQDEHQNHS TSQDKSQVQG DQIKVMDQSN LSMTAHNKSK
ERVSQKEIEL QREKEKEQQK LKEQQEKQKE KEKQQKNESN SLQAIILKLL EFPPFSKPDI
IYLLATVCQS LESPVFVNQN LIYRAFFENK LIYNHAFMKL TYKFGDLLLT CLDKNDQPVT
IKFLDFFDDP RLESGANYQR QFEYIKNELN LIANLCLSRN TLACKTFQQT FLFNKTLPFV
ENSNLKEEIR AVFLKLIRVL YIDQEPYQTQ KRPELVREII YDKSILTTKL IKQDGGILSM
LKMNANNYVS FEEIQKRQLE PLISKDTILY QTMRVKKLKQ QQINWERIQK EQAIDESEVE
ESEEVKKFLQ SLIKILIQHI QESAQKLTSL KQGRLIYNIL TLEVIQIVKL IFQFGFFNYE
YIKPPNQHTK KSQAIMREIE KQIKNSEIEQ IIQLLAQLLE YDEQYNQALE NANVQRKYIE
NKLKRDEKKK KNAFDDLANL GNINLDMMNL LDGAEKQKKE RKIIHQDIEM EIINDPLFRK
VKQLKKILDK CSNKTFSIKQ EDQFTQYEVQ IKMEICEIFI LMLGMRQDFL IDNAIDFFKQ
QFVPYQVSMI DENHNYTDLL PELGIEVGED VDSIQTMKEY CEKFQTVRNF DIILDRPFYE
TLILSLFFST NAKLSNKIVE LIEKYSSQRY DLVQNLTELQ VVVSMETIAF YKKWSRLLNK
LKRNIPNCQA WLQLDTPQKL NGRNETNFQK NLKLVKKIID VFQENAGDNQ RMKIKQRIFK
HVGGFDSMLE LMLSCMIMII NNRQVFTFKE APTSFSQYQQ HLAKLILQLL ECILQIMVFF
GKNSIENQEL VFHKVVPHLT KYRRNNFNQS QFITDLLNDN PKLTQHINRD REIEYFFKLI
KKHGRYTEFI DFFLIILKNA ESNKTGQSNV LSMHIINFVL DKKYFEFCNP FVPQPKLKGK
SLFYQHKPQS SYLGKFIIML AQCLKNYIGV SLTYRAQQTF KLNLLLESLV QISSEERETA
FEQFNQLEVK TCIFEIIMVV LERAEKKNLE IMSCSEKIQE FLVLESQFLN SRQQFSNAQL
IYLFQKQSPF LLQYFKAFYK DAGAKLFQNA EQSKIERKKI QEYGKAFLNA LNHMSQKTIM
DDVPKISMVE DLCRALKIDI PKSFRRPVNS DDEIDDDVEE QEDETDDKAK QISMDVSNEN
THQKGSFTTG PPLVNENTAR AFLQKFKSLK AKQLQTDKKD NEDSESKQIN YYWQLFVSLL
SDNEQVHEAI KEEKQIFANS VWNISQMFQS DIKSDQKDLV LNQEDVVKNL LNYIQYWQVN
AADKKSVLFI FKALKQILKN PFRSDDLDEL RERQEILNKL NATKILMQLL WSEDENDLQY
LTTLLSLFCM MLKKGNLVVQ TTILEYSKSN QECEKLYFKL NLIIANYINS NPAELKQQGK
LQTKLICKTL QFMQLLCEGH NLQLQEYLHQ QTNSKTSYDL VLQIVKLQQC IKIDNKNYGI
VTQCFDTITE VIQGPCKTNQ IALSNSKFME YVVDVLSENE KLFETQEIQK KQEAKLLGVI
FKQVQTQKKE FKSFNQMGQT KEQQGIKRNK IMDPTKPYNL TLHLAKLARL KLKALISLVS
LVECCDLQDN LILRIIRAIP IRVLTNNMSR QYFKDEYKEE LFGRAEQLIV LTEEEEKYEL
VVEIGFYIYI LMQIFVASKK GKDILQEDIE MREILNEFDV DRADEQSTGL FSGISKLGGQ
MLQVGLGGLQ KFKQGIEEVG KTDEDRRKEK EAQELEEKKK NKELLKNSIR FFKKNSCSIE
IVREEKVYQV FFPKLPYCHQ LPKDLKTEFH DEVNRSSAKT KLNYLMTKSE SIIKTMKHEE
YLRILFNINP IFGAIASQGK LWELCLFLTT IAINLIILFS YSQFLVPDQY LDNDSRIQYY
RLYEPRLLWY DQLSITKQII LILGILDLAF SSLIVFFFAL KRAPLKVYHI WVGFFSTQGF
FKIIIRLIKN SLVSIFVLLQ DFEILYYSAY ILAGIVGLAA HPFFFCVHLM DFLKLDQLKT
VVQAIWKPKV ELGLALMLLI IIEYYFNILA WIVFYNQYPA SGESGQEYCN EFWRCLITTF
DWTFKFTGSI GAHLQDPATL EELQKQAVLQ GDEDASYDYV NADQTAIYYE RFFFDNLFNI
MLVFILLNMI QGIIIDTFSS LREDLAEKNK DMEFKCFVCG FDMETLDKSS DSDKGFAFHI
KYEHHMWNYV FYFAYLQFKD PTEYDGNETF VSNKMENLDL GWLPIKKAKC ITDENQEDKK
KLEQLDLLNK KADKIEEDLK KQTEKVEKIY KSLLPE
//
