ID A0DK90_PARTE Unreviewed; 492 AA.
AC A0DK90;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
GN ORFNames=GSPATT00017786001 {ECO:0000313|EMBL:CAK83457.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK83457.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK83457.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK83457.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
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DR EMBL; CT868474; CAK83457.1; -; Genomic_DNA.
DR RefSeq; XP_001450854.1; XM_001450817.1.
DR AlphaFoldDB; A0DK90; -.
DR STRING; 5888.A0DK90; -.
DR EnsemblProtists; CAK83457; CAK83457; GSPATT00017786001.
DR GeneID; 5036639; -.
DR KEGG; ptm:GSPATT00017786001; -.
DR eggNOG; KOG2517; Eukaryota.
DR HOGENOM; CLU_009281_2_3_1; -.
DR InParanoid; A0DK90; -.
DR OMA; HKTDATN; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0004370; F:glycerol kinase activity; IBA:GO_Central.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006071; P:glycerol metabolic process; IBA:GO_Central.
DR GO; GO:0046167; P:glycerol-3-phosphate biosynthetic process; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IBA:GO_Central.
DR GO; GO:0006641; P:triglyceride metabolic process; IBA:GO_Central.
DR CDD; cd07769; FGGY_GK; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|RuleBase:RU003733};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW Transferase {ECO:0000256|RuleBase:RU003733}.
FT DOMAIN 5..248
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 261..446
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 492 AA; 55994 MW; 7D3F0D3884D5AEDD CRC64;
MQSVIGSIDS STTGTRFTIC NLNGEQLSYH YITHKQITPH QGWLEHDPNE ILNNTIECIK
QAHKKMDGVH KLVTIGVTNQ RETVVAWNKH TAIPYMNAIV WSDTRTHDIC QEYLNKYPKN
YFQQKTGLPI NTYFSSYKLQ WMIQNNQALR DDLNSGNVLF GTIDCWIVWN LTREQNHLTD
VTNASRTNLM NLHTLQWDED LLNQFNIPKN CLPQIKASNS NFGSLKIEEY EGVPINCVLG
DQQAAAIGHA LFHEGDCKNT QGSGLFIMAN IGENIKISDF GLLTTVLYQK ENEKPVYAFE
GAVESGGQLF NWAKDKLQWF ENWEQLSQST VNAEDNGGVY IVPAFSGLFT PFWNFDATGT
MIGLSYYTTK DHIRRAILES VCYRTKDVIK AMEQSGIKIN KIHVDGGLTK NKELMQLQAD
ITQKKLVYPE IIESTASGAA MFAAVGLNLL TEQQIIQNMK VQQIYEGKKS YEKQYKQWEL
AVNCALQFKK IE
//
