ID A0JY24_ARTS2 Unreviewed; 354 AA.
AC A0JY24;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Transketolase, central region {ECO:0000313|EMBL:ABK03944.1};
GN OrderedLocusNames=Arth_2565 {ECO:0000313|EMBL:ABK03944.1};
OS Arthrobacter sp. (strain FB24).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=290399 {ECO:0000313|EMBL:ABK03944.1, ECO:0000313|Proteomes:UP000000754};
RN [1] {ECO:0000313|Proteomes:UP000000754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FB24 {ECO:0000313|Proteomes:UP000000754};
RX PubMed=24501649; DOI=10.4056/sigs.4438185;
RA Nakatsu C.H., Barabote R., Thompson S., Bruce D., Detter C., Brettin T.,
RA Han C., Beasley F., Chen W., Konopka A., Xie G.;
RT "Complete genome sequence of Arthrobacter sp. strain FB24.";
RL Stand. Genomic Sci. 9:106-116(2013).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CP000454; ABK03944.1; -; Genomic_DNA.
DR AlphaFoldDB; A0JY24; -.
DR STRING; 290399.Arth_2565; -.
DR KEGG; art:Arth_2565; -.
DR eggNOG; COG0022; Bacteria.
DR HOGENOM; CLU_012907_1_0_11; -.
DR OrthoDB; 3457658at2; -.
DR Proteomes; UP000000754; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000754}.
FT DOMAIN 24..199
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
FT REGION 203..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 354 AA; 38285 MW; 241AD95A8D84ACC4 CRC64;
MSSAILEGGA GMADGTPRRG VEQLSMQQAL NRALDEVLAG NPKSLVFGED CGRLGGVFRI
TDGLQAKYGP GRVFDTPLAE SGILGMSVGL AMAGFHPIPE VQFDGFAYPA INQIVCQIAR
MNYRSRGTMP MPITLRVPSF GGIRAPEHHG ESLEALFAHV PGLKVVSPSN PHEAYHLLKY
AATRPDPVIF MEPKSRYWQK GEVDFDSADP SGSPAGGPPT GAKVMREGRH LTLVAWGAMV
ARCLQVAELA AEDGIDVEVL DLRWLKPIDE AALAASVRKT RRAVVVHEAP RTSGLGAEVA
QLITQSCFDT LKAPVERITG FDVPYPSGDL EDEYIPNIDR ILFGIQRVLE YRRG
//
