ID A0LFB2_SYNFM Unreviewed; 295 AA.
AC A0LFB2;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=3'-5' exonuclease {ECO:0000313|EMBL:ABK16114.1};
GN OrderedLocusNames=Sfum_0414 {ECO:0000313|EMBL:ABK16114.1};
OS Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC Bacteria; Thermodesulfobacteriota; Syntrophobacteria; Syntrophobacterales;
OC Syntrophobacteraceae; Syntrophobacter.
OX NCBI_TaxID=335543 {ECO:0000313|EMBL:ABK16114.1, ECO:0000313|Proteomes:UP000001784};
RN [1] {ECO:0000313|EMBL:ABK16114.1, ECO:0000313|Proteomes:UP000001784}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10017 / MPOB {ECO:0000313|Proteomes:UP000001784};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J., Sieber J.,
RA Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000478; ABK16114.1; -; Genomic_DNA.
DR RefSeq; WP_011697287.1; NC_008554.1.
DR AlphaFoldDB; A0LFB2; -.
DR STRING; 335543.Sfum_0414; -.
DR KEGG; sfu:Sfum_0414; -.
DR eggNOG; COG0349; Bacteria.
DR HOGENOM; CLU_042387_1_0_7; -.
DR InParanoid; A0LFB2; -.
DR Proteomes; UP000001784; Chromosome.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:InterPro.
DR CDD; cd06142; RNaseD_exo; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR045092; Rrp6-like.
DR PANTHER; PTHR12124:SF47; EXOSOME COMPONENT 10; 1.
DR PANTHER; PTHR12124; POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF00570; HRDC; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:ABK16114.1};
KW Hydrolase {ECO:0000313|EMBL:ABK16114.1};
KW Nuclease {ECO:0000313|EMBL:ABK16114.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001784}.
FT DOMAIN 211..292
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 295 AA; 33930 MW; 1FB0CB20E8E32BEE CRC64;
MNPVVVIEKP SELDALVRQL STARHLAVDT ESNSFYAYFD RVCLIQISSP ERDYIIDPLS
LKDLSVLGRL FENPRIEKVL HAASNDVLGL RRDFQFRFNG LFDTAIACKL LGYKQLGLSK
ILETHFGVSL NKRWQRYDWG KRPLVPDQLD YARLDTHYLI ALRHMLAADL QSRELWAEAC
EAFEKASEQQ VPEKTFHPRG FLQINGARSL DAAGKSILKA LYMFREKEAR RRDRAPFRIM
SNEALLRLAD ARPDSVDEIS RIKGLPRSFH DPKAASFLIE IIRQNNNSND TEARE
//
