ID A0LKE0_SYNFM Unreviewed; 565 AA.
AC A0LKE0;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:ABK17892.1};
GN OrderedLocusNames=Sfum_2210 {ECO:0000313|EMBL:ABK17892.1};
OS Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC Bacteria; Thermodesulfobacteriota; Syntrophobacteria; Syntrophobacterales;
OC Syntrophobacteraceae; Syntrophobacter.
OX NCBI_TaxID=335543 {ECO:0000313|EMBL:ABK17892.1, ECO:0000313|Proteomes:UP000001784};
RN [1] {ECO:0000313|EMBL:ABK17892.1, ECO:0000313|Proteomes:UP000001784}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10017 / MPOB {ECO:0000313|Proteomes:UP000001784};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J., Sieber J.,
RA Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP000478; ABK17892.1; -; Genomic_DNA.
DR RefSeq; WP_011699061.1; NC_008554.1.
DR AlphaFoldDB; A0LKE0; -.
DR STRING; 335543.Sfum_2210; -.
DR KEGG; sfu:Sfum_2210; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_021572_0_0_7; -.
DR InParanoid; A0LKE0; -.
DR OrthoDB; 9762608at2; -.
DR Proteomes; UP000001784; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001784}.
FT DOMAIN 289..508
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 565 AA; 64283 MW; 863D46D818930846 CRC64;
MNTKEETEDR RIALVFPPAI HPTGPPLGAA ALKAFLLSRD PSRSVRVFDL NLAHYEQALR
WMREGRLKMS LRKMDHASSA ERVADTFRFL RGEKGLDAFA SLPDYDEHAG FFSSFETVLN
GLFDSFARKL LASLRVPPLA DEYFRELIRP VKRFRPRLAG FSILFSQQVY FAAILARYLK
EDDATIVFGG ATLSVMPRPE VLLADRTVVP VGETRAGIPF GRFIDGLIVG EGETGIDALA
GAGGCDPAHV PGLVYSDAGR VRRNGPRRIE KLEELPLPDF DDCNPAAYLS PMPILPYLSS
RGCFWRRCAF CTHRKTYLAY REEPPEYTVS RLAELSRRHG AVLFSLVDEM IHPHRFSRLA
RKILEAGLDI RYAAYAKPTA RFDAALLGRL HASGARVVMW GVESGNQRVL DLMRKGTRAD
RMGRVLEDAR RAGIRNLVFV MFGFPSETRQ EREDTMRFLE AHRDSIDALS KSRFILLEGA
DMLETPERFH ITRVLDRTDR DPVSVAFDYE VSDGPTQAEA RRFYEERMPY LNRFGRSPFF
PRYRDHMLVH AVLRDSPRES TQHHE
//
