ID   A0P6D2_9PROT            Unreviewed;       747 AA.
AC   A0P6D2;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Orn/Lys/Arg decarboxylase, major region:Orn/Lys/Arg decarboxylase, C-terminal {ECO:0000313|EMBL:EAV47092.1};
GN   ORFNames=MB2181_03425 {ECO:0000313|EMBL:EAV47092.1};
OS   Methylophilales bacterium HTCC2181.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales; OM43 clade.
OX   NCBI_TaxID=383631 {ECO:0000313|EMBL:EAV47092.1, ECO:0000313|Proteomes:UP000054262};
RN   [1] {ECO:0000313|EMBL:EAV47092.1, ECO:0000313|Proteomes:UP000054262}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC2181 {ECO:0000313|EMBL:EAV47092.1,
RC   ECO:0000313|Proteomes:UP000054262};
RA   Giovannoni S., Vergin K., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA   Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC       {ECO:0000256|ARBA:ARBA00010671}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAV47092.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAUX01000001; EAV47092.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0P6D2; -.
DR   OrthoDB; 9761189at2; -.
DR   Proteomes; UP000054262; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR005308; OKR_de-COase_N.
DR   InterPro; IPR011193; Orn/lys/arg_de-COase.
DR   InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR   InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR   InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR45229:SF3; BIODEGRADATIVE ARGININE DECARBOXYLASE; 1.
DR   PANTHER; PTHR45229; CONSTITUTIVE ORNITHINE DECARBOXYLASE; 1.
DR   Pfam; PF01276; OKR_DC_1; 1.
DR   Pfam; PF03711; OKR_DC_1_C; 1.
DR   Pfam; PF03709; OKR_DC_1_N; 1.
DR   PIRSF; PIRSF009393; Orn_decarb; 1.
DR   SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00703; OKR_DC_1; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR009393-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054262}.
FT   DOMAIN          387..401
FT                   /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT                   attachment site"
FT                   /evidence="ECO:0000259|PROSITE:PS00703"
FT   MOD_RES         392
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR009393-1"
SQ   SEQUENCE   747 AA;  84766 MW;  FD1490BBF2A15D66 CRC64;
     MKFKFPIIII DEDYRSENSS GLGIRVLAES IEKEDFEVIG VTSYVDLSSF AQQQSRASAF
     ILAIDDEEFI EENPKALESL SKFVEEIRYR NDEIPIFLHG ETKTSRHIPN KILKELNGFI
     HMYEDTPEFV AKYIVREAKT YLESLAPPFF RALTHYASDG SYSWHCPGHS GGVAFLKSPV
     GQMFHQFFGE NMLRADVCNA VEELGQLLDH TGPVEASEKN AARIYKADHC YFVTNGTSTS
     NKMVWNSTVA PGDIVVVDRN CHKSVLHAII MTGAIPIFLM PTRNHFGIIG PIPKEEFSWD
     RIKEKIKNNP FIEDKEVKPR VLTITQSTYD GILYNVEEIK EMLDGKIGAL HFDEAWLPHA
     SFHDFYGDYH AIGADRPRCE ESLIFSTQST HKMLAGLSQA SQILVQDATN NKLDKELFNE
     SYLMHSSTSP QYSIIASCDV AAAMMEEPGG NALVEESIME ALNFRRAMRK VDQEWGDGWW
     FKVWGPDDLS EEGIEERAAW MLNKNEKWHG FGNLAPNFNM LDPIKATIIT PGLNVDGEFD
     GKLGIPAVIV TKYLAEHGVI VEKTGLYSFF IMFTIGITKG RWNTLVAALQ QFKDDYDKNQ
     PIWKVLPEFS QKFPIYESIG LKDLSDKIHE IFKENDIARL TTEMYLSDMV PAMKPANAFA
     KMAHKEIQRV PIDDLEGRIT AVLLTPYPPG IPLLIPGERF NKIIVDYLKF ARTFNEKFPG
     FETDNHGLIK NYIDGKLTYY VDCVVDN
//