ID A0PCF6_GASAC Unreviewed; 170 AA.
AC A0PCF6;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Taste receptor family 1, type 2 {ECO:0000313|EMBL:BAF37299.1};
DE Flags: Fragment;
GN Name=T1R2 {ECO:0000313|EMBL:BAF37299.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|EMBL:BAF37299.1};
RN [1] {ECO:0000313|EMBL:BAF37299.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17467198; DOI=10.1016/j.gene.2007.03.015;
RA Hashiguchi Y., Furuta Y., Kawahara R., Nishida M.;
RT "Diversification and adaptive evolution of putative sweet taste receptors
RT in threespine stickleback.";
RL Gene 396:170-179(2007).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AB284584; BAF37299.1; -; Genomic_DNA.
DR AlphaFoldDB; A0PCF6; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF441; TASTE RECEPTOR TYPE 1 MEMBER 2B-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:BAF37299.1};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 62..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 63..158
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAF37299.1"
FT NON_TER 170
FT /evidence="ECO:0000313|EMBL:BAF37299.1"
SQ SEQUENCE 170 AA; 18818 MW; 09142344037B30F5 CRC64;
SKKMPDGIHR CCFKCEICSK GTYLKKTEDP YECINCKDTE WSAAGSTSCN LRELEFVPFT
DIGAILIMVG AWALVVLTVA MSVLFAINYN TPVVRSAGGP MCFLIFGCLC LSNVSVFFYF
GKPTGSSCVM RLLPFLMFYT VCLSCFVVRS FQIVFHFQNG CQVPKAPQCG
//
