ID A0PPW7_MYCUA Unreviewed; 337 AA.
AC A0PPW7;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=Cobalamin-independent methionine synthase MetE C-terminal/archaeal domain-containing protein {ECO:0000259|Pfam:PF01717};
GN OrderedLocusNames=MUL_1930 {ECO:0000313|EMBL:ABL04386.1};
OS Mycobacterium ulcerans (strain Agy99).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium ulcerans group.
OX NCBI_TaxID=362242 {ECO:0000313|EMBL:ABL04386.1, ECO:0000313|Proteomes:UP000000765};
RN [1] {ECO:0000313|EMBL:ABL04386.1, ECO:0000313|Proteomes:UP000000765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Agy99 {ECO:0000313|EMBL:ABL04386.1,
RC ECO:0000313|Proteomes:UP000000765};
RX PubMed=17210928; DOI=10.1101/gr.5942807;
RA Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T.,
RA Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J.,
RA Johnson P.D., Davies J.K., Jenkin G.A., Small P.L., Jones L.M., Tekaia F.,
RA Laval F., Daffe M., Parkhill J., Cole S.T.;
RT "Reductive evolution and niche adaptation inferred from the genome of
RT Mycobacterium ulcerans, the causative agent of Buruli ulcer.";
RL Genome Res. 17:192-200(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000325; ABL04386.1; -; Genomic_DNA.
DR RefSeq; WP_011740005.1; NC_008611.1.
DR AlphaFoldDB; A0PPW7; -.
DR GeneID; 72434829; -.
DR KEGG; mul:MUL_1930; -.
DR eggNOG; COG0620; Bacteria.
DR HOGENOM; CLU_065357_0_0_11; -.
DR Proteomes; UP000000765; Chromosome.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR CDD; cd03310; CIMS_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR Pfam; PF01717; Meth_synt_2; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 4: Predicted;
FT DOMAIN 4..328
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 337 AA; 34282 MW; 356A0766202F277A CRC64;
MSVFATATGV GSWPGILARP AAEVVVGELA DALAYLVELP ARGVGADMLG RAGALLVDLA
LDTVPRGYRI VPRPGAVTRR AISMLNEDMD ALEEAWETAG LRGGGRVVKV QAPGPITLAA
GVELSNGHRA IIDPGAVRDL AASLGEGVAA HRAELARRLD TPVVVQFDEP TLPAALEGRL
TGVTSLAPVA ALDEAVALGL LDTCVEAAGA DVALHSCAAA LPWDLLQRSG ISAVSVDVAT
LRAADLDSIA AFIDSGRTVV LGVVPASVPD RRPSAEEVAA DVVAVTDRLG FGRTVLRDHV
GVAPGCGLAG ATPQWARTAI GLAREAAEGL ARDPDAI
//
