ID A0PXK1_CLONN Unreviewed; 448 AA.
AC A0PXK1;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Hydrogenase {ECO:0000313|EMBL:ABK60397.1};
DE EC=1.12.7.2 {ECO:0000313|EMBL:ABK60397.1};
GN OrderedLocusNames=NT01CX_1006 {ECO:0000313|EMBL:ABK60397.1};
OS Clostridium novyi (strain NT).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=386415 {ECO:0000313|EMBL:ABK60397.1, ECO:0000313|Proteomes:UP000008220};
RN [1] {ECO:0000313|EMBL:ABK60397.1, ECO:0000313|Proteomes:UP000008220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NT {ECO:0000313|EMBL:ABK60397.1,
RC ECO:0000313|Proteomes:UP000008220};
RX PubMed=17115055; DOI=10.1038/nbt1256;
RA Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA Zhou S.;
RT "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT NT.";
RL Nat. Biotechnol. 24:1573-1580(2006).
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DR EMBL; CP000382; ABK60397.1; -; Genomic_DNA.
DR RefSeq; WP_011721124.1; NC_008593.1.
DR AlphaFoldDB; A0PXK1; -.
DR STRING; 386415.NT01CX_1006; -.
DR KEGG; cno:NT01CX_1006; -.
DR PATRIC; fig|386415.7.peg.129; -.
DR eggNOG; COG1143; Bacteria.
DR eggNOG; COG4624; Bacteria.
DR HOGENOM; CLU_039046_2_0_9; -.
DR Proteomes; UP000008220; Chromosome.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.20; -; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR PANTHER; PTHR11615:SF368; HYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:ABK60397.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008220}.
FT DOMAIN 110..140
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 448 AA; 50053 MW; A8A433FC0D2D3CC1 CRC64;
MNKKFDNLFK KLVKAYYNDN FEETVTHILS KETEDKEYLS KVISSLCGVN IEFDDNFIIN
LKKAIGNYEI RHKIVHKVHD CSMDCSKDGE KTRCQKSCPF DAILVDKNTS TTYISLGKCV
DCGFCVDACP TGSILDKVEF IPLIDLLNKE DIVIAAVAPS IIGQFGENVS MNKLRTAFKK
LGFTDMVEVA FFADMLTLNE ATEFNKNVNS IDDFMITSCC CPMWMAMLKK SFKELLPHVS
PSVSPMIAAG KVLKKLNPKC KVVFIGPCIA KKSEAKEKDL AGIIDFVLTY KETKDIFDAL
NIHPEELKED NTIEYSSKQG LIYGFTGGVS KAICDTIETL FPDRKDLLKT TKANGIKECR
EVLSLLKQGD LDSNFIEGMG CVGGCVGGPG TIISKEEGQK SLSNLANNSE ISISTQNHWM
KNILNNLDIY SIKDFENKEK TEIFHRNL
//
