ID A0Q6B7_FRATN Unreviewed; 209 AA.
AC A0Q6B7;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=GDSL-like Lipase/Acylhydrolase family protein {ECO:0000313|EMBL:AJI60727.1};
DE SubName: Full=GDSL-like lipolytic enzyme {ECO:0000313|EMBL:ABK89782.1};
GN OrderedLocusNames=FTN_0894 {ECO:0000313|EMBL:ABK89782.1};
GN ORFNames=AW25_1124 {ECO:0000313|EMBL:AJI60727.1};
OS Francisella tularensis subsp. novicida (strain U112).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Francisellaceae; Francisella.
OX NCBI_TaxID=401614 {ECO:0000313|EMBL:ABK89782.1, ECO:0000313|Proteomes:UP000000762};
RN [1] {ECO:0000313|EMBL:ABK89782.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=U112 {ECO:0000313|EMBL:ABK89782.1};
RA Brittnacher M., Rohmer L., Zhou Y., Abmayr S., D'Argenio D., Bovee D.,
RA Chang J., Chen J., Drees B., Ernst R., Fong C., Forsman M., Gallagher L.,
RA Gallis B., Gillett W., Goodlett D., Guina T., Guenthner D., Haugen E.,
RA Hayden H., Jacobs M., Kang A., Larson Freeman T., Levy R., Lim R.,
RA Manoil C., Olson M.V., Radey M., Shaffer S., Svensson K., Taylor G.,
RA Wasnick M., Kaul R., Miller S.I.;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000000762}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=U112 {ECO:0000313|Proteomes:UP000000762};
RX PubMed=17550600; DOI=10.1186/gb-2007-8-6-r102;
RA Rohmer L., Fong C., Abmayr S., Wasnick M., Larson Freeman T.J., Radey M.,
RA Guina T., Svensson K., Hayden H.S., Jacobs M., Gallagher L.A., Manoil C.,
RA Ernst R.K., Drees B., Buckley D., Haugen E., Bovee D., Zhou Y., Chang J.,
RA Levy R., Lim R., Gillett W., Guenthener D., Kang A., Shaffer S.A.,
RA Taylor G., Chen J., Gallis B., D'Argenio D.A., Forsman M., Olson M.V.,
RA Goodlett D.R., Kaul R., Miller S.I., Brittnacher M.J.;
RT "Comparison of Francisella tularensis genomes reveals evolutionary events
RT associated with the emergence of human pathogenic strains.";
RL Genome Biol. 8:R102.1-R102.16(2007).
RN [3] {ECO:0000313|EMBL:AJI60727.1, ECO:0000313|Proteomes:UP000031872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=U112 {ECO:0000313|EMBL:AJI60727.1,
RC ECO:0000313|Proteomes:UP000031872};
RX PubMed=25931589;
RA Johnson S.L., Daligault H.E., Davenport K.W., Coyne S.R., Frey K.G.,
RA Koroleva G.I., Broomall S.M., Bishop-Lilly K.A., Bruce D.C., Chertkov O.,
RA Freitas T., Jaissle J., Ladner J.T., Rosenzweig C.N., Gibbons H.S.,
RA Palacios G.F., Redden C.L., Xu Y., Minogue T.D., Chain P.S.;
RT "Genome sequencing of 18 francisella strains to aid in assay development
RT and testing.";
RL Genome Announc. 3:0-0(2015).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000439; ABK89782.1; -; Genomic_DNA.
DR EMBL; CP009633; AJI60727.1; -; Genomic_DNA.
DR RefSeq; WP_003033792.1; NZ_CP009633.1.
DR AlphaFoldDB; A0Q6B7; -.
DR KEGG; ftn:FTN_0894; -.
DR KEGG; ftx:AW25_1124; -.
DR BioCyc; FTUL401614:G1G75-932-MONOMER; -.
DR Proteomes; UP000000762; Chromosome.
DR Proteomes; UP000031872; Chromosome.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd01822; Lysophospholipase_L1_like; 1.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR008265; Lipase_GDSL_AS.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR30383; THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1; 1.
DR PANTHER; PTHR30383:SF5; THIOESTERASE 1_PROTEASE 1_LYSOPHOSPHOLIPASE L1; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
DR PROSITE; PS01098; LIPASE_GDSL_SER; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AJI60727.1}.
FT DOMAIN 43..192
FT /note="SGNH hydrolase-type esterase"
FT /evidence="ECO:0000259|Pfam:PF13472"
SQ SEQUENCE 209 AA; 23151 MW; C30533C2EFAB040A CRC64;
MRKIILAIVL AVLVYLVYYV FFENNYNNWP IVNAKPQGET IVAFGDSLTA GYGVDKKDNY
PSQLAKMLNQ PVINMGISGE TTQQALLRIN KVIAKKPKIV LITLGGNDLK KKIPAGEAFD
NLKQIVNILQ ANGALVVIGG IDIPYYKNDY AQDYIEFAKN NGCLLVPNIL SGLIGHSELM
IDAVHPNAKG YNIMAKQFYD VIDKYLAQK
//
