ID A0QSN4_MYCS2 Unreviewed; 460 AA.
AC A0QSN4;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=ATP-dependent RNA helicase {ECO:0000313|EMBL:ABK72176.1};
GN OrderedLocusNames=MSMEG_1540 {ECO:0000313|EMBL:ABK72176.1};
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK72176.1, ECO:0000313|Proteomes:UP000000757};
RN [1] {ECO:0000313|EMBL:ABK72176.1, ECO:0000313|Proteomes:UP000000757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000480; ABK72176.1; -; Genomic_DNA.
DR RefSeq; WP_011727728.1; NZ_SIJM01000016.1.
DR RefSeq; YP_885922.1; NC_008596.1.
DR AlphaFoldDB; A0QSN4; -.
DR STRING; 246196.MSMEG_1540; -.
DR PaxDb; 246196-MSMEI_1504; -.
DR GeneID; 66732997; -.
DR KEGG; msm:MSMEG_1540; -.
DR PATRIC; fig|246196.19.peg.1525; -.
DR eggNOG; COG0513; Bacteria.
DR OrthoDB; 9805696at2; -.
DR Proteomes; UP000000757; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ABK72176.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000757}.
FT DOMAIN 5..33
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 36..211
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 237..385
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 385..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 5..33
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 403..417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 460 AA; 48606 MW; 8F0428A21D0BA388 CRC64;
MSAQKTFAEL GLPAELVSTL AANGVTTPFP IQAATLPDSL NGRDVLGRGR TGSGKTYAFL
LPLVARLATS GTPRDAGKPR AVILAPTREL VTQIEASLAP LAAATGLRTV NIFGGVGAGP
QIAALRRGVD IVIACPGRLE DHVQSRHADL SSVEVTILDE ADHMADLGFL PGVKRLLDRT
PKHCQRLLFS ATLDAGVDVL VKRYLHDPVV HSVDSAQSPV SAMVHHVLHV DNAARINVVA
DLAAAPGRTI VFARTKHGAK NLTRQLNSRG ISAVELHGNL SQNARTRNLT AFSDGSATVM
VATDIAARGI HVDDVSLVVH ADPPVEHKAY LHRSGRTARA GNEGTVVTLM LDAQVHDVRN
LTRKAGVKPT ITRISGLDHP VLREIAPGER VFGEPIRTEP AATPSRPRST QPRRSRPQGS
GRPGRSGHGA QSEGAAAARG GAHRGGRGRR PRRSNESSAR
//
