ID A0QUK0_MYCS2 Unreviewed; 382 AA.
AC A0QUK0;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Thiolase {ECO:0000313|EMBL:ABK73835.1};
GN OrderedLocusNames=MSMEG_2236 {ECO:0000313|EMBL:ABK73835.1};
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK73835.1, ECO:0000313|Proteomes:UP000000757};
RN [1] {ECO:0000313|EMBL:ABK73835.1, ECO:0000313|Proteomes:UP000000757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP000480; ABK73835.1; -; Genomic_DNA.
DR RefSeq; WP_011728242.1; NZ_SIJM01000022.1.
DR RefSeq; YP_886588.1; NC_008596.1.
DR AlphaFoldDB; A0QUK0; -.
DR STRING; 246196.MSMEG_2236; -.
DR PaxDb; 246196-MSMEI_2182; -.
DR GeneID; 66733655; -.
DR KEGG; msm:MSMEG_2236; -.
DR PATRIC; fig|246196.19.peg.2202; -.
DR eggNOG; COG0183; Bacteria.
DR OrthoDB; 9785768at2; -.
DR Proteomes; UP000000757; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00829; SCP-x_thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR PANTHER; PTHR42870; ACETYL-COA C-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR42870:SF1; NON-SPECIFIC LIPID-TRANSFER PROTEIN-LIKE 2; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000000757};
KW Transferase {ECO:0000256|RuleBase:RU003557}.
FT DOMAIN 5..174
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 248..353
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
SQ SEQUENCE 382 AA; 40561 MW; BD0A2E74E1BA75BF CRC64;
MSHDVAIIGV GIHPFGRFEG KTAMQMGVDA IFAAVADAGV DWKDIGAATG GSWTVANPDA
IVGMVGLSGI PFTNVFNACA TAASATKVCA DGIRLGDYDI GIAVGLDKHP RGAFTEDPAL
VGMPKWYAEN GQYLTTQFFG MKANRYLHDH NISRRTLARV AAKNFRNGAL NPNAFRRKPI
SEDDILNSTM LNYPLTQYMF CAPDEGAAAV VMCRADIAHR YTDKPVYLKA VEVRTRRYGA
YEVNTTCAPV EEDVAPTVYA ARAAFEKAGV APEDVDVIQL QDTDAGAEII HMAECGFCAH
GDQEKLLADG ATEIGGSLPV NTDGGLIANG EPIGASGLRQ IHELVRQLRG EAGDRQVPGE
PKVGFAQLYG APGTAGATIL TR
//
