ID A0QWE7_MYCS2 Unreviewed; 255 AA.
AC A0QWE7;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=DNA-binding response regulator, PhoP family protein {ECO:0000313|EMBL:ABK73706.1};
GN OrderedLocusNames=MSMEG_2916 {ECO:0000313|EMBL:ABK73706.1};
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK73706.1, ECO:0000313|Proteomes:UP000000757};
RN [1] {ECO:0000313|EMBL:ABK73706.1, ECO:0000313|Proteomes:UP000000757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000480; ABK73706.1; -; Genomic_DNA.
DR RefSeq; YP_887235.1; NC_008596.1.
DR AlphaFoldDB; A0QWE7; -.
DR STRING; 246196.MSMEG_2916; -.
DR PaxDb; 246196-MSMEI_2843; -.
DR KEGG; msm:MSMEG_2916; -.
DR PATRIC; fig|246196.19.peg.2879; -.
DR eggNOG; COG0745; Bacteria.
DR OrthoDB; 4760923at2; -.
DR Proteomes; UP000000757; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.250.690; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR039420; WalR-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR48111; REGULATOR OF RPOS; 1.
DR PANTHER; PTHR48111:SF28; TRANSCRIPTIONAL REGULATORY PROTEIN TCRX-RELATED; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000000757}.
FT DOMAIN 31..145
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 156..253
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 156..253
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT MOD_RES 80
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 255 AA; 28698 MW; E1C2720886EBE9F6 CRC64;
MTSAQLKNPR PRRAILGQLP RMYRPDGSPI RVLLVDDERA LTNLVQMALQ YEGWVIDVAH
DAAQAVEKYR ANLPDLLVLD IMLPDTDGLG VLEQIRSFGT YTPTLFLTAR DSVADRVEGL
TAGGDDYMTK PFSLEELVAR LRGLLRRTAY LTPAADETLR VGDLTLDASS HTVTRGDTPI
ALTSTEFQLL RVLMRHPRKA LSRDDILRQV WEYDFGGRTS IVDLYVSYLR KKIDTGREPM
IHTVRGVGYM LRPAD
//
