ID A0QYU5_MYCS2 Unreviewed; 252 AA.
AC A0QYU5;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=RNA methyltransferase, TrmH family protein {ECO:0000313|EMBL:ABK71160.1};
GN OrderedLocusNames=MSMEG_3790 {ECO:0000313|EMBL:ABK71160.1};
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK71160.1, ECO:0000313|Proteomes:UP000000757};
RN [1] {ECO:0000313|EMBL:ABK71160.1, ECO:0000313|Proteomes:UP000000757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000480; ABK71160.1; -; Genomic_DNA.
DR RefSeq; WP_011729329.1; NZ_SIJM01000005.1.
DR RefSeq; YP_888083.1; NC_008596.1.
DR AlphaFoldDB; A0QYU5; -.
DR STRING; 246196.MSMEG_3790; -.
DR PaxDb; 246196-MSMEI_3702; -.
DR GeneID; 66735160; -.
DR KEGG; msm:MSMEG_3790; -.
DR PATRIC; fig|246196.19.peg.3729; -.
DR eggNOG; COG0566; Bacteria.
DR OrthoDB; 9794400at2; -.
DR Proteomes; UP000000757; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18095; SpoU-like_rRNA-MTase; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR PANTHER; PTHR43191:SF16; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR43191; RRNA METHYLTRANSFERASE 3; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:ABK71160.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000757};
KW Transferase {ECO:0000313|EMBL:ABK71160.1}.
FT DOMAIN 20..88
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
SQ SEQUENCE 252 AA; 26372 MW; 729D63B1A93E323F CRC64;
MVAAVKLHRH VGRRRAARFL AEGPNLVEAA LRRGLVSEVF ATEAALDRFG ALLADAPVTP
VTERAAKALS DTVTPVGLVA VCRLPEVSLD DVLAGPAGLI AVPVQLSEPG NAGTLIRVAD
AMGAAAVVLA GNSVDPYNSK CLRASAGSIF SIPVISDPDE ARVVQRLRDA GLRVLATTVD
GEADLDDPDL EAELTEPTAW LFGPEAHGLS TDLAAMAHRR VQIPMPGHAE SLNIASAASI
CLYQSARAQR RR
//
