ID A0QZH0_MYCS2 Unreviewed; 199 AA.
AC A0QZH0;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=TetR-family protein transcriptional regulator {ECO:0000313|EMBL:ABK70913.1};
GN OrderedLocusNames=MSMEG_4022 {ECO:0000313|EMBL:ABK70913.1};
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK70913.1, ECO:0000313|Proteomes:UP000000757};
RN [1] {ECO:0000313|EMBL:ABK70913.1, ECO:0000313|Proteomes:UP000000757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000480; ABK70913.1; -; Genomic_DNA.
DR RefSeq; WP_011729483.1; NZ_SIJM01000044.1.
DR RefSeq; YP_888308.1; NC_008596.1.
DR AlphaFoldDB; A0QZH0; -.
DR STRING; 246196.MSMEG_4022; -.
DR PaxDb; 246196-MSMEI_3926; -.
DR GeneID; 66735379; -.
DR KEGG; msm:MSMEG_4022; -.
DR PATRIC; fig|246196.19.peg.3958; -.
DR eggNOG; COG1309; Bacteria.
DR OrthoDB; 5242520at2; -.
DR Proteomes; UP000000757; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF226; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1474C; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000000757};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 13..73
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 36..55
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 199 AA; 21634 MW; 0BEDC17844125EBB CRC64;
MTRRRSTAPS KGDRRREAVL DAAEALLSTT GYHAMTIADI ADGAGITRGA LYFYFGSKQE
VITALFARCV EVLHEKSRAA AADAASGAAA IDMAMERTEA LWREHGVVMR TAIDLASTVE
ELDRLWADTA DLFIDAIRAI LENMGVPAGS GVDESSSLAK TLCWMIERNF YQASRISNAE
LAKASRTCAE IWRRAARSA
//
