ID A0R3N6_MYCS2 Unreviewed; 669 AA.
AC A0R3N6;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=Conserved integral membrane protein {ECO:0000313|EMBL:ABK69984.1};
GN OrderedLocusNames=MSMEG_5537 {ECO:0000313|EMBL:ABK69984.1};
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK69984.1, ECO:0000313|Proteomes:UP000000757};
RN [1] {ECO:0000313|EMBL:ABK69984.1, ECO:0000313|Proteomes:UP000000757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
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DR EMBL; CP000480; ABK69984.1; -; Genomic_DNA.
DR RefSeq; WP_011730604.1; NZ_SIJM01000006.1.
DR RefSeq; YP_889774.1; NC_008596.1.
DR AlphaFoldDB; A0R3N6; -.
DR STRING; 246196.MSMEG_5537; -.
DR PaxDb; 246196-MSMEI_5384; -.
DR GeneID; 66736835; -.
DR KEGG; msm:MSMEG_5537; -.
DR PATRIC; fig|246196.19.peg.5396; -.
DR eggNOG; COG1835; Bacteria.
DR eggNOG; COG2755; Bacteria.
DR OrthoDB; 3404679at2; -.
DR Proteomes; UP000000757; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR002656; Acyl_transf_3_dom.
DR InterPro; IPR043968; SGNH.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR23028; ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR23028:SF53; O-ACYLTRANSFERASE HOMOLOG; 1.
DR Pfam; PF01757; Acyl_transf_3; 1.
DR Pfam; PF19040; SGNH; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000757};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..369
FT /note="Acyltransferase 3"
FT /evidence="ECO:0000259|Pfam:PF01757"
FT DOMAIN 441..654
FT /note="SGNH"
FT /evidence="ECO:0000259|Pfam:PF19040"
SQ SEQUENCE 669 AA; 72626 MW; 6C20C98827E5A964 CRC64;
MTAAPVRAAG RRRTLPARGE IPALDGIRAI AVLLVLAGHA GVPGVAGGFI GVDIFFVLSG
FLITSLLLDE FARTGRVDLK GFWIRRARRL LPALLVMTLA VVAARELFPP DAVTSLRDDA
VAAFFWVANW AFVAQQADYF SQGAPPSPLQ HTWSLGVEEQ YYLVWPLLVL FAVLLLRRRG
ARAVRIAVVV IATAGAAASA ACAIVAVNTD TLNRVYFGTD FRAQGLLLGA AAAALLVRDW
SALTVSGTLI RARWRRWIAW VLPVFGLAVL GAAAHLATGD AEDFRHGLLI IVAAAAVLVI
VPVALDQYGW VARALGWRPL VALGAISYGV YLWHWPLFLI LNGERTGLTG WSLVALRFGV
TIALAWVSWR FVEQPVRRWR PQHVPMLPLA AATAATAAVV TLTVVPVTPP QPTPLGPDVM
SAAAVQPDVG AERPVLGPAP ARRAPGTHSV AVFGDSVAWT LMRYLPATPG LAFSNYTTIG
CGIARGGPYR SAGETLNQKP ECDTWPARWT QRIRHDRPDT VLLMIGRWEI VDRKHEGHWT
HIGEDAYDDY LTAELQRALD ILGSTGARVV VTTAPYTRRG ERADGSLYPE DQPSRVRAWN
TILRDVAAKR PNVSVLDFNA KLNPNGAYTA RVDGIRMRSD GVHPTAEAVE WLTPWLVDSL
KKLPPGKPR
//
