ID A0SZK4_TRYCR Unreviewed; 445 AA.
AC A0SZK4;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Thiol transferase Tc52 {ECO:0000313|EMBL:ABK58598.1};
OS Trypanosoma cruzi.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=5693 {ECO:0000313|EMBL:ABK58598.1};
RN [1] {ECO:0000313|EMBL:ABK58598.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Tep23 cl4 {ECO:0000313|EMBL:ABK58598.1};
RX PubMed=17659387; DOI=10.1007/s00436-007-0651-3;
RA Mathieu-Daude F., Bosseno M.F., Garzon E., Lelievre J., Sereno D.,
RA Ouaissi A., Breniere S.F.;
RT "Sequence diversity and differential expression of Tc52 immuno-regulatory
RT protein in Trypanosoma cruzi: potential implications in the biological
RT variability of strains.";
RL Parasitol. Res. 101:1355-1363(2007).
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DR EMBL; EF065176; ABK58598.1; -; mRNA.
DR VEuPathDB; TriTrypDB:BCY84_11003; -.
DR VEuPathDB; TriTrypDB:C3747_167g15; -.
DR VEuPathDB; TriTrypDB:C4B63_113g42; -.
DR VEuPathDB; TriTrypDB:Tc_MARK_3573; -.
DR VEuPathDB; TriTrypDB:TcBrA4_0015080; -.
DR VEuPathDB; TriTrypDB:TcCL_NonESM13180; -.
DR VEuPathDB; TriTrypDB:TcCLB.503419.30; -.
DR VEuPathDB; TriTrypDB:TcCLB.509105.70; -.
DR VEuPathDB; TriTrypDB:TCDM_06784; -.
DR VEuPathDB; TriTrypDB:TcG_07430; -.
DR VEuPathDB; TriTrypDB:TCSYLVIO_004831; -.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd00299; GST_C_family; 2.
DR CDD; cd00570; GST_N_family; 1.
DR Gene3D; 1.20.1050.10; -; 2.
DR Gene3D; 3.40.30.10; Glutaredoxin; 2.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR041695; GST_C_5.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43968; -; 1.
DR PANTHER; PTHR43968:SF6; GLUTATHIONE S-TRANSFERASE OMEGA; 1.
DR Pfam; PF16865; GST_C_5; 2.
DR Pfam; PF13409; GST_N_2; 1.
DR Pfam; PF13417; GST_N_3; 1.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 2.
DR SFLD; SFLDG00358; Main_(cytGST); 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 2.
DR SUPFAM; SSF52833; Thioredoxin-like; 2.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 1.
DR PROSITE; PS50405; GST_CTER; 2.
DR PROSITE; PS50404; GST_NTER; 2.
PE 2: Evidence at transcript level;
KW Transferase {ECO:0000313|EMBL:ABK58598.1}.
FT DOMAIN 2..82
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 88..218
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
FT DOMAIN 226..305
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 286..440
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
SQ SEQUENCE 445 AA; 50718 MW; A65BC104939E12D7 CRC64;
MKALKLFKDR MCPYCQRVLI TAKEKRVKLE EVEVPLGDDM PQWYKELNPR ETVPTLQVDG
KKCMIESDLI SRYIDRISSP ANALIGSSPY QRHRVEFFLS EIGDLIKAYF GLLRDPFNEE
KRKSVDHNTA YIEGIIAEHQ GDGPYFLDDT FSMAEVMVVP FLACFRPVLS YYCGYDIFHE
APRLKKMYVT SMQRTTVKET VLKPEEYIIG FKRKVPTSHV TWSLAPGYVL FVNKYSPFSD
RPRLACALKN IDLPMLEIDL KQLPSWFRWF NQRETVPALL TPQGTHVHES QLIVHYLDDG
FPEHGPALLP KDADGLYHVS FVESNVDYFM DAMFSXIKDP KNRNAKEEFD WAAGELEKLL
AEHQFGEGPF FGGASMNAAD VSLVPMLVHL KACTPDLTEG QDLLANYKLL TAAAEAGLTS
EAGKKVFFSL SEYSSIYKTF LRPSS
//
