ID A0YN57_LYNSP Unreviewed; 545 AA.
AC A0YN57;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:EAW37453.1};
GN ORFNames=L8106_00460 {ECO:0000313|EMBL:EAW37453.1};
OS Lyngbya sp. (strain PCC 8106) (Lyngbya aestuarii (strain CCY9616)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Lyngbya.
OX NCBI_TaxID=313612 {ECO:0000313|EMBL:EAW37453.1, ECO:0000313|Proteomes:UP000000737};
RN [1] {ECO:0000313|EMBL:EAW37453.1, ECO:0000313|Proteomes:UP000000737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC8106 {ECO:0000313|Proteomes:UP000000737};
RA Stal L., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-4/guanylyl cyclase
CC family. {ECO:0000256|RuleBase:RU000405}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAW37453.1}.
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DR EMBL; AAVU01000010; EAW37453.1; -; Genomic_DNA.
DR AlphaFoldDB; A0YN57; -.
DR eggNOG; COG2114; Bacteria.
DR Proteomes; UP000000737; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR018297; A/G_cyclase_CS.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR11920:SF335; GUANYLATE CYCLASE 32E; 1.
DR PANTHER; PTHR11920; GUANYLYL CYCLASE; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS00452; GUANYLATE_CYCLASE_1; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|RuleBase:RU000405};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 26..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 371..498
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 545 AA; 62372 MW; 3DD747498645E5EF CRC64;
MLPLNLLSKD VDKTWNQQSI SRRFKLASVT LLGLVTGVTL TSLISLHFVR QKTELAMVKC
IELQQLVFKM NQELEETNEL EQGFFQEILT LGVERARQNH LKDHDNNIAQ IQNISQQIRQ
LIQEQNSSRN LHKSHDDLST YNQAIEQYHT EFQQSDQIAE ELGNKNIGLI TENQEILQLL
HKNIQYTENV DVIDVYHDLI ASAQAYFLTR KPIEQQNLNL VINQLEELIK QDIYLTVDET
EQALNYLSRS ELYFQKIGLL ENNINQISEK FKKESEVISN QLISLSNEEI QFAHQEIRRT
SQQMTVILLS SVIAMVTLSV VIWRSFQSAL KQLEVEQEKS ERLLLNILPE SIALRLKNKP
ETIADNFEEV TVLFADIAGF TQLSAKISPT ELVNLLNEIF SEFDQITTQN NLEKIKTIGD
AYLVVGGLPN PRSDHAEAIA KLALEMQNKL IEFNQKHDHN LQLRIGINTG PVVAGVIGAK
KFIYDLWGDT VNIASRMESH GIIGEIQVTE ATYQRLQDKY KFEKRGLINV KGKGEMSTYF
LKGIA
//
