ID A0YPN9_LYNSP Unreviewed; 599 AA.
AC A0YPN9;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Penicillin-binding protein, transpeptidase {ECO:0000313|EMBL:EAW36949.1};
GN ORFNames=L8106_21082 {ECO:0000313|EMBL:EAW36949.1};
OS Lyngbya sp. (strain PCC 8106) (Lyngbya aestuarii (strain CCY9616)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Lyngbya.
OX NCBI_TaxID=313612 {ECO:0000313|EMBL:EAW36949.1, ECO:0000313|Proteomes:UP000000737};
RN [1] {ECO:0000313|EMBL:EAW36949.1, ECO:0000313|Proteomes:UP000000737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC8106 {ECO:0000313|Proteomes:UP000000737};
RA Stal L., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAW36949.1}.
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DR EMBL; AAVU01000014; EAW36949.1; -; Genomic_DNA.
DR RefSeq; WP_009784441.1; NZ_AAVU01000014.1.
DR AlphaFoldDB; A0YPN9; -.
DR eggNOG; COG0768; Bacteria.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000000737; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 77..245
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 279..590
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 599 AA; 64652 MW; DCCB83FB4DFD47B4 CRC64;
MVRQLSFTSE TSSIDFLKSP SKSDKRDSRY LYRAVAFILL ITTLMGVSVY RLVGLQLIEG
KQNRIRAEEN RIRLLPIPSN RGRILDRNDQ PLAENHLTRA VYLWPKEQTQ EEWKQSAPQL
SKVLDVPTEE IIAKLEKVNY NSAAPVRIAR YVTPEAFVWI GENALELPGV EIRSDSNRYY
PQGSVASHVL GYIGEATLED LKANPEYPMG MIVGKLGLEA GANEQLAGVW GARLVEVNAQ
NQELRLLGEK PSIGGKGIKL TLDIALQKAA EQGIGYRRGA AVAINVKTGE VLAMASSPRF
NPNTFTKPIS TEEWEDLQGL ENPFLNRTLQ GYPPGSTFKI VSAAAGMGSG KFSPGSMIAT
SASITVGGIT FHEHSGGYGV IGFRDALAFS SNTFFYRLGM AVGAEEIAKW AGRFGIGSTD
LKLLKLGEGS TGFVPTPDNK EEIFGEPWYL GDTITMSIGQ GAVLATPLEL AVMVATAANG
GNRVKPHLLA DMTNTPETKP VPTGLDPQVI NTIKEGLVSV VQYGTGQGMN DGTIPLTGGK
TGTSEVLWQQ SHSLFVGFGP ANNPEIAIAV VIENGGYGSV AAAPVAKQMF QTYFSQKKK
//
